- Limaprost
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- $5.00/ KG
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2026-02-10
- CAS:74397-12-9
- Min. Order: 1KG
- Purity: 99% hplc
- Supply Ability: 500TONS
- Limaprost
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- $74.00 / 1mg
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2026-02-01
- CAS:74397-12-9
- Min. Order:
- Purity: 99.61%
- Supply Ability: 10g
- LIMAPROST
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- $0.00 / 25kg
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2025-12-01
- CAS:74397-12-9
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 10000KGS
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| | LIMAPROST Basic information |
| Product Name: | LIMAPROST | | Synonyms: | (2e,11-alpha,13e,15s,17s)-11,15-dihydroxy-17,20-dimethyl-9-oxoprost-2,13-die;,13e,15s,17s)-;11α,15s-dihydroxy-17s,20-dimethyl-9-oxo-prosta-2e,13e-dien-1-oic acid;17S,20-Dimethyl-trans-D2-PGE1;2-Heptenoic acid, 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S,5S)-3-hydroxy-5-methyl-1-nonenyl]-5-oxocyclopentyl]-, (2E)- (9CI);Prosta-2,13-dien-1-oic acid, 11,15-dihydroxy-17,20-dimethyl-9-oxo-, (2E,11a,13E,15S,17S)-;17α,20-dimethyl-δ2-PGE1, 11α,15S-Dihydroxy-17S,20-dimethyl-9-oxo-prosta-2E,13E-dien-1-oic acid;(2E)-7-[(1R)-2β-[(1E,3S,5S)-3-Hydroxy-5-methyl-1-nonenyl]-3α-hydroxy-5-oxocyclopentan-1α-yl]-2-heptenoic acid | | CAS: | 74397-12-9 | | MF: | C22H36O5 | | MW: | 380.52 | | EINECS: | | | Product Categories: | Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 74397-12-9.mol |  |
| | LIMAPROST Chemical Properties |
| Melting point | 97-100° | | Boiling point | 550.6±50.0 °C(Predicted) | | density | 1.118 | | storage temp. | -20°C | | solubility | DMF: soluble | | pka | 4.78±0.10(Predicted) | | form | crystalline | | color | White to off-white | | InChIKey | OJZYRQPMEIEQFC-UAWLTFRCSA-N | | SMILES | C(O)(=O)/C=C/CCCC[C@H]1C(=O)C[C@@H](O)[C@@H]1/C=C/[C@@H](O)C[C@@H](C)CCCC |
| Hazard Codes | T | | Risk Statements | 25 | | Safety Statements | 36/37/39-45 | | RIDADR | UN 2811 6.1/PG 2 | | WGK Germany | 3 | | RTECS | UK8362500 | | Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials | | Hazard Classifications | Acute Tox. 2 Oral |
| | LIMAPROST Usage And Synthesis |
| Chemical Properties | White crystals, melting point 97-100℃. | | Uses | Limaprost is an analog of Prostaglandin E1 with structural modifications intended to give it a prolonged half-life and greater potency. Limaprost is used as an antianginal. | | Definition | ChEBI: Limaprost is a long-chain fatty acid. | | Biochem/physiol Actions | Limaprost exhibits cytoprotective, vasodilatory, and antiplatelet activity. Limaprost has the potential to treat lumbar spinal canal stenosis (LSCS) and several ischaemic symptoms of thromboangiitis obliterans (TAO). | | in vivo | Limaprost (OP1206) given orally at more than 100 μg/kg relieves Argipressin-induced ST depression of rat electrocardiogram (ECG)[1].
Intra-coronary injection of Limaprost (OP1206; 1-100 ng/kg) in dogs results in a remarkable increase of coronary blood flow without any influence on heart rate, blood pressure, myocardial oxygen consumption and redox potential[1].
Resistance in both large and small vessels of dog coronary artery is decreased by intravenous injection of Limaprost (OP1206; 1-3 mg/kg)[1].
Platelet aggregation, adhesiveness, bleeding time, and thrombocytopenia induced by ADP and collagen infusion in guinea-pigs are inhibited by oral administration of Limaprost (OP1206) at the same doses or doses less than those relieving Argipressin-induced ST depression of ECG[1]. |
| | LIMAPROST Preparation Products And Raw materials |
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