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| | N-Succinimidyl 11-(maleimido)undecanoate Basic information |
| Product Name: | N-Succinimidyl 11-(maleimido)undecanoate | | Synonyms: | Maleimide-(CH2)10-COONHS;N-SUCCINIMIDYL 11-MALEIMIDOUNDECANOATE;N-(11-MALEIMIDOUNDECANOYLOXY)SUCCINIMIDE;11-Maleimidoundecanoic acid N-succinimidyl ester;N-(11-Maleimidoundecanoyloxy)succinimide, N-Succinimidyl 11-maleimidoundecanoate;11-(MaleiMido)undecanoic acid N-hydroxysucciniMide ester;NHS-(CH2)10-Mal (KMUS);1H-Pyrrole-2,5-dione, 1-[11-[(2,5-dioxo-1-pyrrolidinyl)oxy]-11-oxoundecyl]- | | CAS: | 87981-04-2 | | MF: | C19H26N2O6 | | MW: | 378.42 | | EINECS: | | | Product Categories: | | | Mol File: | 87981-04-2.mol |  |
| | N-Succinimidyl 11-(maleimido)undecanoate Chemical Properties |
| Melting point | 90.0 to 94.0 °C | | Boiling point | 520.4±42.0 °C(Predicted) | | density | 1.25±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | pka | -2.20±0.20(Predicted) | | form | powder to crystal | | color | White to Almost white |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | F | 10-21 | | HS Code | 2925.19.9100 |
| | N-Succinimidyl 11-(maleimido)undecanoate Usage And Synthesis |
| Uses | Maleimide-C10-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | Alkyl/ether | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | N-Succinimidyl 11-(maleimido)undecanoate Preparation Products And Raw materials |
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