2-Amino-3-chlorobenzaldehyde

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2-Amino-3-chlorobenzaldehyde Basic information
Product Name:2-Amino-3-chlorobenzaldehyde
Synonyms:2-Amino-3-chlorobenzaldehyde;2-Amino-3-chlorobenzaldehyde 98%;3-Chloroanthranilaldehyde, 2-Chloro-6-formylaniline;Benzaldehyde, 2-amino-3-chloro-
CAS:397322-82-6
MF:C7H6ClNO
MW:155.58
EINECS:
Product Categories:
Mol File:397322-82-6.mol
2-Amino-3-chlorobenzaldehyde Structure
2-Amino-3-chlorobenzaldehyde Chemical Properties
Melting point 30-31 °C
Boiling point 264.3±25.0 °C(Predicted)
density 1.348±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka-1.59±0.10(Predicted)
AppearanceLight yellow to yellow Solid
Safety Information
HS Code 2913000090
MSDS Information
2-Amino-3-chlorobenzaldehyde Usage And Synthesis
Synthesis
(2-Amino-3-chlorophenyl)methanol

61487-25-0

2-Amino-3-chlorobenzaldehyde

397322-82-6

GENERAL METHOD: (2-Amino-3-chlorophenyl)methanol (1.2 g, 7.61 mmol) was dissolved in dichloromethane (20 mL) and manganese dioxide (2.6 g, 30.1 mmol) was added. The reaction mixture was stirred at room temperature for 23 hours under argon protection. After completion of the reaction, the solid catalyst was removed by filtration and the filtrate was concentrated under reduced pressure. The residue was recrystallized by ethyl acetate to give 2-amino-3-chlorobenzaldehyde (1.0 g, 85% yield) as yellow needle-like crystals.

References[1] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 19, p. 5810 - 5831
2-Amino-3-chlorobenzaldehyde Preparation Products And Raw materials
Raw materials(2-Amino-3-chlorophenyl)methanol-->Dichloromethane-->Manganese dioxide
Preparation ProductsCHEMBRDG-BB 4003794
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