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| | Coronalolide Basic information |
| Product Name: | Coronalolide | | Synonyms: | Coronalolide;6aH-Cyclopenta[7,8]cyclopropa[4,4a]naphtho[2,3-b]furan-6a-propanoic acid, 3-[(1R,4E)-1,5-dimethyl-6-oxo-4-hexen-1-yl]tetradecahydro-3a,10b-dimethyl-7-methylene-8-oxo-, (3R,3aR,5aS,6aR,6bR,9aR,10aS,10bS)- | | CAS: | 268214-51-3 | | MF: | C30H42O5 | | MW: | 482.66 | | EINECS: | | | Product Categories: | | | Mol File: | 268214-51-3.mol |  |
| | Coronalolide Chemical Properties |
| Melting point | 82.2-83.1 °C(Solv: dichloromethane (75-09-2); hexane (110-54-3)) | | Boiling point | 646.3±20.0 °C(Predicted) | | density | 1.17±0.1 g/cm3(Predicted) | | pka | 4.69±0.10(Predicted) |
| | Coronalolide Usage And Synthesis |
| Uses | Coronalolide is a natural triterpene with anticancer effects. Coronalolide exhibits a broad cytotoxic activity for human breast (BT474), gastric (KATO-3), lung (CHAGO), colon (SW-620), and liver (Hep-G2) cancer cell lines, with IC50 values of 6.59 μg/mL, 5.85 μg/mL, 5.42 μg/mL, 4.98 μg/mL, and 6.41 μg/mL, respectively[1]. | | References | [1] Thanesuan Nuanyai, et al. Cytotoxic 3,4-seco-cycloartane triterpenes from Gardenia sootepensis. J Nat Prod. 2009 Jun;72(6):1161-4. DOI:10.1021/np900156k |
| | Coronalolide Preparation Products And Raw materials |
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