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| | 4-Fluoro-5-methylbenzene-1,2-diamine Basic information |
| Product Name: | 4-Fluoro-5-methylbenzene-1,2-diamine | | Synonyms: | 4-Fluoro-5-methylbenzene-1,2-diamine;4-Fluoro-5-methylphenylene-1,2-diamine, 4,5-Diamino-2-fluorotoluene;(2-amino-4-fluoro-5-methyl-phenyl)amine;5-Fluoro-4-methylbenzene-1,2-diamine;4-fluoro-5-methyl-1,2-benzenediamine;1,2-Benzenediamine, 4-fluoro-5-methyl-;4-fluoro-5-methylorthobenzenediamine | | CAS: | 97389-11-2 | | MF: | C7H9FN2 | | MW: | 140.16 | | EINECS: | | | Product Categories: | | | Mol File: | 97389-11-2.mol |  |
| | 4-Fluoro-5-methylbenzene-1,2-diamine Chemical Properties |
| Boiling point | 273.5±35.0 °C(Predicted) | | density | 1.224±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | pka | 4.34±0.10(Predicted) | | Appearance | Brown to black Solid |
| HazardClass | IRRITANT | | HS Code | 2921599090 |
| | 4-Fluoro-5-methylbenzene-1,2-diamine Usage And Synthesis |
| Synthesis | Step 4 Synthesis of 5-fluoro-4-methylbenzene-1,2-diamine: 4-fluoro-5-methyl-2-nitroaniline (3.12 g, 0.018 mol), sodium dithionite (Na2S2O4, 9.58 g, 0.055 mol), water (45 mL), and ethanol (90 mL) were added to a 250 mL round bottom flask. The reaction mixture was heated to reflux and kept for 1 hour. Upon completion of the reaction, the solvent was removed by rotary evaporator. The residue was suspended in a mixture of triethylamine (15 mL) and ethyl acetate (300 mL) and subsequently filtered. The filtrate was concentrated under reduced pressure to give 2.1 g (82% yield) of the target product 5-fluoro-4-methylbenzene-1,2-diamine as a light red solid. | | References | [1] Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry, 1985, vol. 39, # 3, p. 213 - 217
[2] Patent: US2010/120741, 2010, A1. Location in patent: Page/Page column 35
[3] Patent: WO2011/112731, 2011, A2. Location in patent: Page/Page column 101 |
| | 4-Fluoro-5-methylbenzene-1,2-diamine Preparation Products And Raw materials |
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