| Company Name: |
Chiba Pharmaceutical Science and technology Co, Ltd.
|
| Tel: |
0531-81313138 13066006660 |
| Email: |
chibapharm@foxmail.com |
| Products Intro: |
Product Name:2-(4-(broMoMethyl)phenyl)-2-Methylpropanenitrile
CAS:1201643-73-3
Purity:98% HPLC Package:5g;10g;25g;100g;250g;500g;1Kg
|
| Company Name: |
Shanghai T&W Pharmaceutical Co., Ltd.
|
| Tel: |
+86 21 61551611 |
| Email: |
|
| Products Intro: |
Product Name:2-(4-(bromomethyl)phenyl)-2-methylpropanenitrile
CAS:1201643-73-3
Purity:98% Package:50kg;25kg;10kg;5kg;500g;500mg;
|
2-(4-(broMoMethyl)phenyl)-2-Methylpropanenitrile manufacturers
|
| | 2-(4-(broMoMethyl)phenyl)-2-Methylpropanenitrile Basic information |
| | 2-(4-(broMoMethyl)phenyl)-2-Methylpropanenitrile Chemical Properties |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| | 2-(4-(broMoMethyl)phenyl)-2-Methylpropanenitrile Usage And Synthesis |
| Synthesis | General procedure for the synthesis of 2-(4-(bromomethyl)phenyl)-2-methylpropionitrile using 2-methyl-2-(p-tolyl)propanenitrile as starting material: to a solution of 2-methyl-2-(p-tolyl)propanenitrile (32 g, 0.2 mol) in carbon tetrachloride (300 ml) was added sequentially N-bromosuccinimide (NBS, 40 g, 0.22 mol) and azobisisobutyronitrile ( AIBN, 1.64 g, 0.01 mol). The reaction mixture was heated to reflux for 2 hours. After completion of the reaction, it was cooled to room temperature and filtered to remove insoluble solids. The filtrate was concentrated to dryness under reduced pressure to give the crude product 2-(4-(bromomethyl)phenyl)-2-methylpropanenitrile (33 g, 70% yield) as a yellow oil. Mass spectrometry (MS) data (m/z): 238,240 (M++H). | | References | [1] Patent: WO2009/155527, 2009, A2. Location in patent: Page/Page column 140-141 |
| | 2-(4-(broMoMethyl)phenyl)-2-Methylpropanenitrile Preparation Products And Raw materials |
|