- TC-DAPK 6
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- $32.00
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2026-07-27
- CAS:315694-89-4
- Purity: 98.73%
- Supply Ability: 10g
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| | TC-DAPK 6 Basic information |
| Product Name: | TC-DAPK 6 | | Synonyms: | TC-DAPK 6;DAPK inhibitor;2-(2-Phenylethenyl)-4-(3-pyridinylmethylene)-5(4H)-oxazolone;2-(2-Phenylethenyl)-4-(3-pyridinylmethylene)-5(4H)-oxazolone TC-DAPK 6;CS-1003;TCDAPK6;DAPK INHIBITOR;5(4H)-Oxazolone, 2-(2-phenylethenyl)-4-(3-pyridinylmethylene)-;(4E)-2-[(E)-2-phenylethenyl]-4-(pyridin-3-ylmethylidene)-1,3-oxazol-5-one | | CAS: | 315694-89-4 | | MF: | C17H12N2O2 | | MW: | 276.29 | | EINECS: | | | Product Categories: | Protein kinase 1 inhibitor | | Mol File: | 315694-89-4.mol |  |
| | TC-DAPK 6 Chemical Properties |
| Boiling point | 439.6±55.0 °C(Predicted) | | density | 1.18±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO : 18.67 mg/mL (67.57 mM; Need ultrasonic and warming)H2O : < 0.1 mg/mL (insoluble) | | form | Powder | | pka | 3.44±0.12(Predicted) | | color | Light yellow to yellow | | InChI | 1S/C17H12N2O2/c20-17-15(11-14-7-4-10-18-12-14)19-16(21-17)9-8-13-5-2-1-3-6-13/h1-12H/b9-8+,15-11+ | | InChIKey | GFGMISOSPOPSHN-QCTDOKRBSA-N | | SMILES | N1=C(OC(=O)\C\1=C/c3cnccc3)\C=C\c2ccccc2 |
| WGK Germany | WGK 2 | | Storage Class | 11 - Combustible Solids |
| | TC-DAPK 6 Usage And Synthesis |
| Uses | TC-DAPK 6 is a potent, ATP-competitive, and highly selective DAPK inhibitor (IC50=69 and 225 nM against DAPK1 and DAPK3, respectively, with 10 μM ATP). | | References | [1] Okamoto M, et al. Identification of death-associated protein kinases inhibitors using structure-based virtual screening. J Med Chem. 2009 Nov 26;52(22):7323-7. DOI:10.1021/jm901191q |
| | TC-DAPK 6 Preparation Products And Raw materials |
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