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| | 2,6-dichloro-N-Methylpyridin-4-aMine Basic information |
| | 2,6-dichloro-N-Methylpyridin-4-aMine Chemical Properties |
| Melting point | 70 °C | | Boiling point | 312.0±37.0 °C(Predicted) | | density | 1.404±0.06 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | pka | 0.79±0.10(Predicted) | | Appearance | White to off-white Solid |
| | 2,6-dichloro-N-Methylpyridin-4-aMine Usage And Synthesis |
| Synthesis | GENERAL STEPS: 2,4,6-Trichloropyridine (20.0 g, 109.63 mmol) was dissolved in anhydrous ethanol (100 mL). An ethanol solution of 33% methylamine (81.9 mL, 657 mmol) was added slowly and dropwise at room temperature. The reaction mixture was stirred continuously at room temperature for 2 weeks. After completion of the reaction, the white precipitate was collected by filtration and washed with methyl tert-butyl ether and deionized water sequentially to afford 2,6-dichloro-4-methylaminopyridine (11.9 g, 61% yield) as white crystals. | | References | [1] Patent: WO2008/92942, 2008, A2. Location in patent: Page/Page column 22
[2] Patent: WO2006/53166, 2006, A1. Location in patent: Page/Page column 57-58
[3] New Journal of Chemistry, 2016, vol. 40, # 11, p. 9194 - 9204
[4] Patent: WO2006/122137, 2006, A1. Location in patent: Page/Page column 71-72
[5] Patent: US2015/57260, 2015, A1. Location in patent: Paragraph 0300; 0331; 0551; 0552 |
| | 2,6-dichloro-N-Methylpyridin-4-aMine Preparation Products And Raw materials |
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