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| | ethyl 3-(tert-butoxycarbonyl(2-cyanoethyl)aMino)propanoate Basic information |
| Product Name: | ethyl 3-(tert-butoxycarbonyl(2-cyanoethyl)aMino)propanoate | | Synonyms: | ethyl 3-(tert-butoxycarbonyl(2-cyanoethyl)aMino)propanoate;tert-butyl 2-(ethoxycarbonyl)ethyl2-cyanoethylcarbamate;N-(2-Cyanoethyl)-N-[(1,1-dimethylethoxy)carbonyl]-β-Alanine Ethyl Ester;β-Alanine, N-(2-cyanoethyl)-N-[(1,1-dimethylethoxy)carbonyl]-, ethyl ester | | CAS: | 266353-22-4 | | MF: | C13H22N2O4 | | MW: | 270.32478 | | EINECS: | | | Product Categories: | | | Mol File: | 266353-22-4.mol |  |
| | ethyl 3-(tert-butoxycarbonyl(2-cyanoethyl)aMino)propanoate Chemical Properties |
| Boiling point | 389.4±35.0 °C(Predicted) | | density | 1.077±0.06 g/cm3(Predicted) | | pka | -1.74±0.70(Predicted) |
| | ethyl 3-(tert-butoxycarbonyl(2-cyanoethyl)aMino)propanoate Usage And Synthesis |
| Uses | N-(2-Cyanoethyl)-N-[(1,1-dimethylethoxy)carbonyl]-β-Alanine Ethyl Ester is an intermediate in the synthesis of GNE-781 (D447825), a derivative of a highly advanced, potent and selective bromodomain inhibitor of cyclic adenosine monophosphate response element binding protein (CBP). Inhibition of the bromodomain of the transcriptional regulator CBP/P300 is an especially interesting new therapeutic approach in oncology. |
| | ethyl 3-(tert-butoxycarbonyl(2-cyanoethyl)aMino)propanoate Preparation Products And Raw materials |
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