| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:N-C16-deoxysphingosine CAS:1246298-56-5 Purity:N-palmitoyl-1-deoxysphingosine (m18:1/16:0), powder Package:1MG Remarks:860456P-1MG
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| Company Name: |
Codow Chemical Co.,Ltd.
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| Tel: |
18620099427 |
| Email: |
amy@howeipharm.com |
| Products Intro: |
Product Name:N-palmitoyl-1-deoxysphingosine (m18:1/16:0) CAS:1246298-56-5 Purity:>99% Package:1MG;2.5MG;5MG;10MG
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| Company Name: |
Chengdu Huachun Technology Co., Ltd
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| Tel: |
400-1166-196 15982826727 |
| Email: |
cdhxsj@163.com |
| Products Intro: |
Product Name:N-palmitoyl-1-deoxysphingosine (m18:1/16:0) CAS:1246298-56-5 Purity:99% HPLC Package:10g;50g;100g;500g;1kg;5kg;25kg
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| | N-palMitoyl-1-deoxysphingosine (M18:1/16:0) Basic information |
| Product Name: | N-palMitoyl-1-deoxysphingosine (M18:1/16:0) | | Synonyms: | N-palMitoyl-1-deoxysphingosine (M18:1/16:0);N-C16-deoxysphingosine;N-PALMITOYL-1-DEOXYSPHINGOSINE (M18:1/16:0);N-C16-DEOXYSPHINGOSINE;Hexadecanamide, N-[(1S,2R,3E)-2-hydroxy-1-methyl-3-heptadecen-1-yl]-;C16 1-Deoxyceramide (m18:1/16:0);N-palMitoyl-1-deoxysphingosine (M18 | | CAS: | 1246298-56-5 | | MF: | C34H67NO2 | | MW: | 521.9 | | EINECS: | | | Product Categories: | | | Mol File: | 1246298-56-5.mol |  |
| | N-palMitoyl-1-deoxysphingosine (M18:1/16:0) Chemical Properties |
| storage temp. | -20°C | | solubility | DMF: >20 mg/ml; DMSO: >20 mg/ml; Ethanol: >30 mg/ml; Ethanol:PBS (pH 7.2) (1:1): 0.5 mg/ml; PBS (pH 7.2): <50μg/ml | | form | A crystalline solid |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | N-palMitoyl-1-deoxysphingosine (M18:1/16:0) Usage And Synthesis |
| Uses | C16 1-Deoxyceramide (m18:1/16:0) (C16:0 1-Deoxyceramide) is a lipid molecule, which is composed of a long-chain fatty acid (16:0) and a 1-deoxysphingoid backbone. Deoxyceramide accumulates under the conditions of obesity and type 2 diabetes (T2D). Deoxyceramide is unable to be further metabolized to more complex sphingolipid, and is toxic when accumulates in the body. Deoxyceramide increases in differentiated adipocytes in vitro[1]. | | References | [1] Hannich JT, et al., Ether lipids, sphingolipids and toxic 1-deoxyceramides as hallmarks for lean and obese type 2 diabetic patients. Acta Physiol (Oxf). 2021 May;232(1):e13610. DOI:10.1111/apha.13610 |
| | N-palMitoyl-1-deoxysphingosine (M18:1/16:0) Preparation Products And Raw materials |
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