| Company Name: |
Codow Chemical Co.,Ltd.
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18620099427 |
| Email: |
amy@howeipharm.com |
| Products Intro: |
Product Name:N-nervonoyl-1-deoxysphingosine (m18:1/24:1)
CAS:1246298-58-7
Purity:>99% Package:1MG;2.5MG;5MG;10MG
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| Company Name: |
Chengdu Huachun Technology Co., Ltd
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| Tel: |
400-1166-196 15982826727 |
| Email: |
cdhxsj@163.com |
| Products Intro: |
Product Name:N-nervonoyl-1-deoxysphingosine (m18:1/24:1)
CAS:1246298-58-7
Purity:99% HPLC Package:10g;50g;100g;500g;1kg;5kg;25kg
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| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
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| Tel: |
400-9205774 |
| Email: |
sales@glpbio.cn |
| Products Intro: |
Product Name:C24:1 1-Deoxyceramide (m18:1/24:1(15Z))
CAS:1246298-58-7
Purity:>98% Package:1mg;10mg;50mg;100mg;
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| | N-nervonoyl-1-deoxysphingosine (M18:1/24:1) Basic information |
| Product Name: | N-nervonoyl-1-deoxysphingosine (M18:1/24:1) | | Synonyms: | N-nervonoyl-1-deoxysphingosine (M18:1/24:1);N-C24:1-deoxysphingosine;N-NERVONOYL-1-DEOXYSPHINGOSINE (M18:1/24:1);N-C24:1-DEOXYSPHINGOSINE;C24:1 1-Deoxyceramide (m18:1/24:1(15Z));15-Tetracosenamide, N-[(1S,2R,3E)-2-hydroxy-1-methyl-3-heptadecen-1-yl]-, (15Z)-;N-nervonoyl-1-deoxysphingosine (M18 | | CAS: | 1246298-58-7 | | MF: | C42H81NO2 | | MW: | 632.1 | | EINECS: | | | Product Categories: | | | Mol File: | 1246298-58-7.mol |  |
| | N-nervonoyl-1-deoxysphingosine (M18:1/24:1) Chemical Properties |
| Boiling point | 717.2±53.0 °C(Predicted) | | density | 0.886±0.06 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | DMF: >20 mg/ml; DMSO: >20 mg/ml; Ethanol: >30mg/ml; Ethanol:PBS (pH 7.2) (1:1): 0.5 mg/ml; PBS (pH 7.2): <50μg/ml | | form | A crystalline solid | | pka | 13.78±0.20(Predicted) |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | N-nervonoyl-1-deoxysphingosine (M18:1/24:1) Usage And Synthesis |
| Description | C24:1 1-Deoxyceramide (m18:1/24:1(15Z)) is a very long-chain atypical ceramide containing a 1-deoxysphingosine (m18:1(4E)) backbone. 1-Deoxysphingolipids are formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis. | | Uses | C24:1 1-Deoxyceramide (m18:1/24:1(15Z)) (C24:1(15Z) 1-Deoxyceramide) is a lipid molecule, which is composed of a long-chain fatty acid (24:1) and a 1-deoxysphingoid backbone. Deoxyceramide accumulates under the conditions of obesity and type 2 diabetes (T2D). Deoxyceramide is unable to be further metabolized to more complex sphingolipid, and is toxic when accumulates in the body. Deoxyceramide increases in differentiated adipocytes in vitro[1]. | | References | [1] Hannich JT, et al., Ether lipids, sphingolipids and toxic 1-deoxyceramides as hallmarks for lean and obese type 2 diabetic patients. Acta Physiol (Oxf). 2021 May;232(1):e13610. DOI:10.1111/apha.13610 |
| | N-nervonoyl-1-deoxysphingosine (M18:1/24:1) Preparation Products And Raw materials |
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