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Sigma-Aldrich |
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021-61415566 800-8193336 |
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orderCN@merckgroup.com |
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| | ANTI-MMP-2 Basic information |
| Product Name: | ANTI-MMP-2 | | Synonyms: | Anti-Matrix Metalloproteinase-2, N-Terminal antibody produced in rabbit;Anti-Matrix Metalloproteinase-2, Propeptide Region antibody produced in rabbit;Anti-Matrix Metalloproteinase-2, Hemopexin Domain antibody produced in rabbit;Anti-Matrix Metalloproteinase-2, C-Terminal antibody produced in rabbit;Anti-Matrix Metalloproteinase-2 antibody produced in rabbit;Anti-Matrix Metalloproteinase-2, Hinge Region antibody produced in rabbit;Anti-72 kDa gelatinase antibody produced in rabbit;Anti-72 kDa type IV collagenase precursor antibody produced in rabbit | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-MMP-2 Structure]() |
| | ANTI-MMP-2 Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution | | biological source | rabbit |
| Hazard Codes | Xn | | Risk Statements | 42 | | Safety Statements | 23-24/25-45 | | WGK Germany | WGK 1 | | Storage Class | 10 - Combustible liquids |
| | ANTI-MMP-2 Usage And Synthesis |
| Uses | All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.
The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit . | | General Description | Matrix metalloproteinase 2 (MMP2) belong to the homologous matrix metalloproteinase (MMP) family. It consists of a homologous cysteine-switch and zinc binding regions. It is synthesized by proliferating skin fibroblasts, specific bronchial epithelial cells, and SV40-transformed lung fibroblasts. | | Biochem/physiol Actions | MMP2 (matrix metalloproteinase 2) is involved in cleaving triple helical type I and type IV collagen as well as degradation of denatured collagens. Mutation of MMP2 enzymatic activity in the serum or fibroblasts leads to the multicentric osteolysis and arthritis syndrome. |
| | ANTI-MMP-2 Preparation Products And Raw materials |
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