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| Product Name: | RUNX1 | | Synonyms: | ANTI-RUNX1 antibody produced in mouse;MONOCLONAL ANTI-PRDM3 antibody produced in mouse;AML1-EVI-1;RUNX1;AML1;AMLCR1;CBFA2;EVI-1 | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![RUNX1 Structure]() |
| | RUNX1 Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution | | biological source | mouse |
| Storage Class | 10 - Combustible liquids |
| | RUNX1 Usage And Synthesis |
| Uses | Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq) | | Biological Activity | RUNX1 plays a vital role in tumour suppression and oncogenic activities. In hematopoiesis, it is involved in hematopoietic development, hematopoietic stem cell homeostasis, and various blood malignancies. It may have clinicopathological impact on the proliferation of human bone marrow cells used in transplantation therapy. |
| | RUNX1 Preparation Products And Raw materials |
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