| Company Name: |
Biolab Reagents
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| Tel: |
027-65279366 18108604356 |
| Email: |
products@biolabreagent.com |
| Products Intro: |
Product Name:IL-34
Purity:95% SDS-PAGE Package:1mg;100ug
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| Company Name: |
ACROBiosystems
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| Tel: |
13121935750 |
| Email: |
jiaxin.zhao@acrobiosystems.com |
| Products Intro: |
Product Name:IL-34
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| Company Name: |
CUSABIO TECHNOLOGY LLC
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| Tel: |
027-87196173 |
| Email: |
cusabio@163.com |
| Products Intro: |
Product Name:IL34
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| Company Name: |
Enzo Biochem Inc
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| Tel: |
Enzo Biochem Inc. 13797054060 |
| Email: |
Enzoname@qq.com |
| Products Intro: |
Product Name:IL34 Human
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| Product Name: | MGC34647 | | Synonyms: | Monoclonal Anti-IL34 antibody produced in mouse;IL-34;C16orf77;IL34;MGC34647;IL-34 human | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![MGC34647 Structure]() |
| | MGC34647 Chemical Properties |
| storage temp. | -20°C | | form | lyophilized | | biological source | mouse |
| Hazard Codes | Xi | | Risk Statements | 36 | | Safety Statements | 26 | | WGK Germany | WGK 1 | | Storage Class | 10 - Combustible liquids | | Hazard Classifications | Eye Irrit. 2
STOT SE 3 |
| | MGC34647 Usage And Synthesis |
| Uses | IL-34 is a ligand for colony-stimulating factor-1 receptor (CSF1R), which also binds to CSF-1. It specifically binds CD14+ monocytes, promotes survival and proliferation of human peripheral blood monocytes, and stimulates macrophage colony formation by human bone marrow cells. IL-34, like human CSF-1 stimulates phosphorylation of MAPK1/ERK2 and MAPK3/ERK1. | | Biological Activity | IL-34 is a homodimeric cytokine th at is expressed in a range of tissues including spleen, heart, brain, liver, kidney, lung, ovary, thymus, testis, small intestine, prostate and colon. Recombinant human IL-34 is a 52.5 kDa homodimeric glycoprotein consisting of 460 amino acid residues, including a C-terminal His-Tag. | | Description | IL34 Human Recombinant produced in CHO cells is a glycosylated homodimeric polypeptide chain containing 228 amino acids and having a total molecular mass of 26kDa.
IL34 is fused to a 6 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques. | | Source | CHO cells | | Background | Interleukin 34 (IL34) is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor and is a part of a group of cytokines called interleukins. IL34 increases growth or survival of immune cells known as monocytes. IL34 protein obtains its activity by binding the Colony stimulating factor 1 receptor. Interleukin 34 has also a potential part in viral infection, the adaptive immune response and bone marrow cell proliferation. Furthermore, IL34 plays an important role in innate immunity and in inflammatory processes. |
| | MGC34647 Preparation Products And Raw materials |
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