2-PHENYLPROPIONIC ACID

2-PHENYLPROPIONIC ACID Suppliers list

Company Name:	Hebei Chuanghai Biotechnology Co., Ltd
Tel:	+8617732866630
Email:	abby@chuanghaibio.com
Products Intro:	Product Name:2-PHENYLPROPIONIC ACID CAS:492-37-5 Purity:99% Package:1kg;1.00;USD

Company Name:	Shaanxi Dideu Medichem Co. Ltd
Tel:	+86-29-81139210 +86-18192627656
Email:	1059@dideu.com
Products Intro:	Product Name:2-PHENYLPROPIONIC ACID CAS:492-37-5 Purity:95% Package:1KG;1USD\|25KG;25USD\|100KG;100USD

Company Name:	Zhengzhou Anbu Chem Co.,Ltd
Tel:	+86-0371-88006763; +8615988602810
Email:	sales@anbuchem.com
Products Intro:	Product Name:2-PHENYLPROPIONIC ACID CAS:492-37-5 Purity:98% Package:1KG

Company Name:	Henan Fengda Chemical Co., Ltd
Tel:	+86-371-86557731 +86-13613820652
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Products Intro:	Product Name: 2-PHENYLPROPIONIC ACID CAS:492-37-5 Purity:99% Package:1KG;5USD\|1000KG;0.1USD

Company Name:	airuikechemical co., ltd.
Tel:	+86-18353166132
Email:	sales02@airuikechemical.com
Products Intro:	Product Name:DL-2-Phenylpropionic acid CAS:492-37-5 Purity:99.99% Package:1g;0.00;USD\|5g;0.00;USD\|25g;0.00;USD

2-PHENYLPROPIONIC ACID manufacturers

2-PHENYLPROPIONIC ACID Basic information

Product Name:	2-PHENYLPROPIONIC ACID
Synonyms:	Benzeneacetic acid, .alpha.-methyl-;(n)-2-phenylpropionic acid;(n)-à-methylphenylacetic acid;2-HENYLPROPIONIC ACID;2-PHENYLPROPINICACID;dl-PPA;α-methyl-α-toluic acid;2-PHENYLPROPIONIC ACID 98%
CAS:	492-37-5
MF:	C9H10O2
MW:	150.17
EINECS:	207-752-0
Product Categories:	Carboxylic Acids;Aliphatics;Carboxylic Acids;Organic acids;Pharmaceutical Intermediates;DDQ
Mol File:	492-37-5.mol

2-PHENYLPROPIONIC ACID Chemical Properties

Melting point	5 °C
Boiling point	260-262 °C (lit.)
density	1.1 g/mL at 25 °C (lit.)
refractive index	n20/D 1.522(lit.)
Fp	>230 °F
storage temp.	Sealed in dry,Room Temperature
solubility	9.9g/l
form	Liquid
pka	4.34±0.10(Predicted)
color	Clear pale yellow to yellow
PH	3 (5g/l, H2O, 20℃)
Water Solubility	10 g/L (20 ºC)
BRN	1863558
LogP	1.699 (est)
CAS DataBase Reference	492-37-5(CAS DataBase Reference)
NIST Chemistry Reference	Benzeneacetic acid, «alpha»-methyl-(492-37-5)
EPA Substance Registry System	Benzeneacetic acid, .alpha.-methyl- (492-37-5)

Safety Information

MSDS Information

2-PHENYLPROPIONIC ACID Usage And Synthesis

Chemical Properties	clear pale yellow to yellow liquid
Uses	2-Phenylpropionic acid is used in the preparation of ibuprofen derivatives for their anti-inflammatory activity. Also used in nucleation inhibitors in Dutch resolution of diastereomers.
Definition	ChEBI: A 2-arylpropionic acid carrying a phenyl group at position 2. It is a metabolite of alpha-methylstyrene (AMS), a volatile hydrocarbon.
Synthesis Reference(s)	Journal of the American Chemical Society, 99, p. 182, 1977 DOI: 10.1021/ja00443a033 The Journal of Organic Chemistry, 51, p. 4354, 1986 DOI: 10.1021/jo00373a005 Tetrahedron Letters, 21, p. 581, 1980 DOI: 10.1016/S0040-4039(01)85562-3
Synthesis	2-Phenylpropionic acid is prepared: 1) from Benzyl cyanide by Metbylation with Methyl iodide and Sodamide to produce alpha-Phenylpropionitrile, from which the acid is produced by acid hydrolysis. 2) from Acetophenone cyanhydrin with Hydriodic acid.
Purification Methods	Fractionally distil the acid, or recrystallise it from pet ether (b 40-60o) with strong cooling (see references below). [Beilstein 9 II 348.]

2-PHENYLPROPIONIC ACID Preparation Products And Raw materials

Raw materials

Tag:2-PHENYLPROPIONIC ACID(492-37-5) Related Product Information

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