| Company Name: |
shlmai |
| Tel: |
021-67680335 13052188602 |
| Email: |
sale1@shlmai.net |
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| Product Name: | hSPL | | Synonyms: | SP-lyase 1;hSPL;Sphingosine-1-phosphate lyase1 Active human;SGPL1 | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![hSPL Structure]() |
| storage temp. | -70°C | | form | aqueous solution | | biological source | human |
| WGK Germany | WGK 1 | | Storage Class | 12 - Non Combustible Liquids |
| Uses | Useful for the study of biochemical function. | | Biological Activity | SGPL1 (sphingosine-1-phosphate lyase 1) enzyme is involved in the synthesis of long-chain aliphatic aldehydes which occurs during several metabolic processes, such as peroxisomal α-oxidation of 3-methyl-branched fatty acids and 2-hydroxy long-chain fatty acids, microsomal oxidation of long-chain alcohols, prenylated protein degradation in the lysosomes, microsomal degradation of phosphorylated sphingoid bases, attack of plasmalogens by myeloperoxidase (MPO)-derived hypochlorous acid, and degradation of (lyso)plasmalogens in the microsomes.s This protein shows reduced expression in OSCC (oral squamous cell carcinoma), colon and prostate cancers, and this is associated with poor prognosis. |
| | hSPL Preparation Products And Raw materials |
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