| Company Name: |
Hubei Yangxin Medical Technology Co., Ltd.
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| Tel: |
15374522761 |
| Email: |
3003392093@yongstandards.com |
| Products Intro: |
Product Name:Arformoterol-d3
CAS:1198353-13-7
Purity:99%+ HPLC Package:10mg;25mg;50mg;100mg
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| Company Name: |
Hefei Molake Biotechnology Co., Ltd.
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| Tel: |
0551-66336380 18956014586 |
| Email: |
983438788@qq.com |
| Products Intro: |
Product Name:Formoterol-d3
CAS:1198353-13-7
Purity:98% Package:10mg,100mg,1g,10g
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| Company Name: |
CHINA ISOTOPE CO., LIMITED
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| Tel: |
02151600108 13062666369 |
| Email: |
info@isotopechem.com |
| Products Intro: |
Product Name:(R.R)-Formoterol-d3 ((R.R)-Arformoterol-d3)
CAS:1198353-13-7
Purity:1mg Package:1mg Remarks:RMCF56013-1mg
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| Company Name: |
TLC Pharmaceutical Standards Ltd.
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| Tel: |
18012923235 |
| Email: |
chinasales04@tlcstandards.com.cn |
| Products Intro: |
Product Name:(R,R)-Formoterol-d3 (Arformoterol-d3)
CAS:1198353-13-7
Purity:95%+ HPLC Package:10mg;25mg;50mg;100mg
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| | FORMOTEROL-D3 Basic information |
| Product Name: | FORMOTEROL-D3 | | Synonyms: | FORMOTEROL-D3;(R,R)-Formoterol-d3 ((R,R)-Arformoterol-d3);Arformoterol-d3;(R,R)-Formoterol-d3 (Arformoterol-d3) | | CAS: | 1198353-13-7 | | MF: | C19H24N2O4 | | MW: | 344.41 | | EINECS: | | | Product Categories: | | | Mol File: | 1198353-13-7.mol |  |
| | FORMOTEROL-D3 Chemical Properties |
| | FORMOTEROL-D3 Usage And Synthesis |
| Uses | Formoterol-d3 is deuterium labeled Arformoterol. Arformoterol ((R,R)-Formoterol), the (R,R)-enantiomer of Formoterol, is a long-acting β2-adrenergic receptor (β2-AR) agonist, with a Kd of 2.9 nM. Arformoterol can be used for the research of chronic obstructive pulmonary disease (COPD)[1][2]. | | References | [1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110
[2] Handley DA, et, al. Biological actions of formoterol isomers. Pulm Pharmacol Ther. 2002;15(2):135-45. DOI:10.1006/pupt.2001.0327
[3] Cazzola M, et, al. Arformoterol tartrate in the treatment of COPD. Expert Rev Respir Med. 2010 Apr;4(2):155-62. DOI:10.1586/ers.10.16
[4] Song W, et, al. Postexposure administration of a {beta}2-agonist decreases chlorine-induced airway hyperreactivity in mice. Am J Respir Cell Mol Biol. 2011 Jul;45(1):88-94. DOI:10.1165/rcmb.2010-0226OC |
| | FORMOTEROL-D3 Preparation Products And Raw materials |
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