3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-5-trifluoromethyl-arabinouridine
| 中文名称 | 3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-5-trifluoromethyl-arabinouridine |
|---|---|
| 中文同义词 | 化合物 3',5'-DI-O-BENZOYL-2'-DEOXY-2'-FLUORO-5-TRIFLUOROMETHYL-ARABINOURIDINE;1-[3,5-氧-苯甲酰基-2-脱氧-2-氟-β-D-阿拉伯糖呋喃糖基]-5-(三氟甲基)-2,4(1H,3H)-嘧啶二酮];[3',5'-氧-苯甲酰基-2'-脱氧-2'-氟-5-三氟甲基-阿拉伯呋喃糖尿苷 |
| 英文名称 | 3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-5-trifluoromethyl-arabinouridine |
| 英文同义词 | 3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-5-trifluoromethyl-arabinouridine;2,4(1H,3H)-Pyrimidinedione, 1-[3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl]-5-(trifluoromethyl)- (9CI);3’,5’-Di-O-benzoyl-2’-deoxy-2’-fluoro-5-trifluoromethyl-arabinouridine;1-[3,5-Di-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl]-5-(trifluoromethyl)-2,4(1H,3H)-pyrimidinedione |
| CAS号 | 117311-99-6 |
| 分子式 | C24H18F4N2O7 |
| 分子量 | 522.41 |
| EINECS号 | |
| 相关类别 | 核苷 |
| Mol文件 | 117311-99-6.mol |
| 结构式 |  |
3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-5-trifluoromethyl-arabinouridine 性质
| 密度 | 1.52±0.1 g/cm3(Predicted) |
|---|---|
| 酸度系数(pKa) | 7.75±0.10(Predicted) |
3,5-Di-O-benzoyl-2-deoxy-2-fluoro-5-trifluoromethyl-arabinouridine 是一种嘌呤核苷类似物。嘌呤核苷类似物具有广泛的抗肿瘤活性，靶向惰性淋巴系统恶性肿瘤。这一过程中的抗癌机制依赖于抑制 DNA 合成，诱导细胞凋亡 (apoptosis) 等。