- N3-PEG3-Br
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- $0.00 / 1g
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2026-02-05
- CAS:1446282-43-4
- Min. Order: 1g
- Purity: 98%
- Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
- Azido-PEG3-Br
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- $0.00 / 1g
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2025-06-07
- CAS:1446282-43-4
- Min. Order: 1g
- Purity: >98.00%
- Supply Ability: 1g
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| | Bromo-PEG3-azide Basic information |
| Product Name: | Bromo-PEG3-azide | | Synonyms: | Bromo-PEG3-azide;Bromo-PEG4-azide;Br-PEG3-N3;N3-PEG3-CH2CH2Br;1-Azido-2-(2-[2-(2-bromoethoxy)ethoxy]ethoxy)ethane;Azido-PEG3-Br;N3-PEG3-Br;N3-PEG3-CH2CH2Br/Ethane, 1-(2-azidoethoxy)-2-[2-(2-bromoethoxy)ethoxy]- | | CAS: | 1446282-43-4 | | MF: | C8H17BrN3O3+ | | MW: | 283.14288 | | EINECS: | | | Product Categories: | peg | | Mol File: | 1446282-43-4.mol |  |
| | Bromo-PEG3-azide Chemical Properties |
| storage temp. | Storage temp. 2-8°C | | solubility | Soluble in DMSO, DCM, DMF | | form | clear liquid | | color | Colorless to Light orange to Yellow |
| | Bromo-PEG3-azide Usage And Synthesis |
| Description | Bromo-PEG3-azide is a PEG linker containing a bromide group and an azide group. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. | | Uses | Bromo-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Bromo-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Bromo-PEG3-azide Preparation Products And Raw materials |
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