| Company Name: |
S.Z. PhyStandard Bio-Tech. Co., Ltd.
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| Tel: |
0755-4000505016 13380397412 |
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3001272453@qq.com |
| Products Intro: |
Product Name:Tandospirone Impurity Ⅰ
CAS:87721-89-9
Purity:98% HPLC Package:10mg;25mg;50mg;100mg
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| Company Name: |
Shanghai Kewel Chemical Co., Ltd.
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| Tel: |
021-64609169 18901607656 |
| Email: |
greensnown@163.com |
| Products Intro: |
Product Name:Tandospirone Impurity Ⅰ
CAS:87721-89-9
Purity:95+ HPLC; Package:10mg;25mg;50mg;100mg
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| Company Name: |
Shanghai Changyan Chem & Tech Co., Ltd.
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| Tel: |
021-20242659 18930833303 |
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Sales@changyanchem.cn |
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Product Name:(3aR,4R,7S,7aS)-2-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]hexahydro-1H-4,7-methanoisoindole-1,3-dione
CAS:87721-89-9
Purity:95% HPLC Package:5KG;1KG;500G;100G;50G
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| Company Name: |
Shanghai Zhen Li Biological Technology Co., Ltd
|
| Tel: |
021-16621358918; 18516310516 |
| Email: |
zhenlipharma888@163.com |
| Products Intro: |
Product Name:(3aR,4R,7S,7aS)-2-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]hexahydro-1H-4,7-methanoisoindole-1,3-dione
CAS:87721-89-9
Purity:95 Package:1g m
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| | (3aR,4R,7S,7aS)-2-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]hexahydro-1H-4,7-methanoisoindole-1,3-dione Basic information |
| Product Name: | (3aR,4R,7S,7aS)-2-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]hexahydro-1H-4,7-methanoisoindole-1,3-dione | | Synonyms: | (3aR,4R,7S,7aS)-2-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]hexahydro-1H-4,7-methanoisoindole-1,3-dione;Tandospirone impurity Ⅰ;Tandospirone Impurity 1;Tandospirone Impurity 19;Tandospirone Impurity 22;4,7-Methano-1H-isoindole-1,3(2H)-dione, hexahydro-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-, (3aR,4R,7S,7aS)-rel-;rel-(3aR,4R,7S,7aS)-2-(4-(4-(Pyrimidin-2-yl)piperazin-1-yl)butyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione;Tandospirone Impurity Ⅰ | | CAS: | 87721-89-9 | | MF: | C21H29N5O2 | | MW: | 383.49 | | EINECS: | | | Product Categories: | | | Mol File: | 87721-89-9.mol | ![(3aR,4R,7S,7aS)-2-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]hexahydro-1H-4,7-methanoisoindole-1,3-dione Structure](CAS/20180703/GIF/87721-89-9.gif) |
| | (3aR,4R,7S,7aS)-2-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]hexahydro-1H-4,7-methanoisoindole-1,3-dione Chemical Properties |
| Boiling point | 613.9±65.0 °C(Predicted) | | density | 1.239±0.06 g/cm3(Predicted) | | pka | 7.71±0.10(Predicted) |
| | (3aR,4R,7S,7aS)-2-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]hexahydro-1H-4,7-methanoisoindole-1,3-dione Usage And Synthesis |
| Uses | endo-Tandospirone is an isomer of Tandospirone, which is a selective anxiolytic agent, an anxiety inhibitor. Tandospirone is compared to Buspirone and Diazepam, other anxiolytic agents, and it is suggested that Tandospirone has more anxiolytic activity and anxio-selectivity than the former agents. |
| | (3aR,4R,7S,7aS)-2-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]hexahydro-1H-4,7-methanoisoindole-1,3-dione Preparation Products And Raw materials |
| Raw materials | 4,7-Methano-1H-isoindole-1,3(2H)-dione, 2-(4-bromobutyl)hexahydro-, (3aR,4R,7S,7aS)-rel--->1-Piperazinebutanenitrile, 4-(2-pyrimidinyl)--->NORBORNANE-2EXO,3EXO-DICARBOXYLIC ACID-ANHYDRIDE-->1-(2-Pyrimidinyl)-4-(4-aminobutyl)piperazine-->CIS-5-NORBORNENE-EXO-2,3-DICARBOXYLIC ANHYDRIDE-->2-(1-Piperazinyl)pyrimidine |
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