| Company Name: |
Alfa Chemistry |
| Tel: |
+1-5166625404; |
| Email: |
Info@alfa-chemistry.com |
CASPASE-9 manufacturers
- CASPASE-9
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2026-08-05
- CAS:265294-58-4
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 1000kg
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| | CASPASE-9 Basic information |
| Product Name: | CASPASE-9 | | Synonyms: | ICE-LAP6;FULL-LENGTH CASPASE-9;CASPASE-9;CASPASE-9 (HUMAN) (ACTIVE) (RECOMBINANT);CASPASE-9 HUMAN, RECOMBINANT;CASPASE-9, HUMAN;CASPASE 9 PROTEIN;CASPASE-9, HUMAN, RECOMBINANT, E COLI | | CAS: | 265294-58-4 | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![CASPASE-9 Structure]() |
| | CASPASE-9 Chemical Properties |
| storage temp. | -70°C | | solubility | PBS with 15% glycerol: 1units/μL | | form | lyophilized | | Specific Activity | ≥400units/mg protein |
| WGK Germany | WGK 1 | | Storage Class | 12 - Non Combustible Liquids |
| | CASPASE-9 Usage And Synthesis |
| Biological Activity | When cells receive apoptotic stimuli, such as activation of the TNFα/Fas cell surface receptor, caspase 8 activation, Bid processing and its translocation to the mitochondria ensue. As a result mitochondria release cytochrome c which then binds to Apaf-1, the mammalian Ced-4 homologue, together with dATP. The resultant complex recruits caspase 9 leading to its activation. It then cleaves downstream caspases such as caspase 3, 6, and 7, initiating the caspase cascade. Caspase 9 exhibits basal activity. It can be further activated via interaction of its N-terminal prodomain with the activator protein Apaf-1 in the presence of cytochrome c and dATP. Caspases have been implicated in many disorders including cancer, inflammatory disease, neurodegenerative diseases, stroke and myocardial infarction. |
| | CASPASE-9 Preparation Products And Raw materials |
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