- ARS-853
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- $153.00 / 1mg
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2025-05-26
- CAS:1629268-00-3
- Min. Order:
- Purity: 96.64%
- Supply Ability: 10g
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| | ARS-853 Basic information |
| Product Name: | ARS-853 | | Synonyms: | ARS-853;ARS-853 (ARS853);CS-2646;2-Propen-1-one, 1-[3-[4-[2-[[4-chloro-2-hydroxy-5-(1-methylcyclopropyl)phenyl]amino]acetyl]-1-piperazinyl]-1-azetidinyl]-;1-(3-(4-((4-chloro-2-hydroxy-5-(1-methylcyclopropyl)phenyl)glycyl)piperazin-1-yl)azetidin-1-yl)prop-2-en-1-one;ARS 853,ARS-853,KRAS,Apoptosis,cancer,mutant,state,inhibit,Inhibitor,inactive,Ras,selective,covalent,ARS853,G12C;ARS-853, 10 mM in DMSO | | CAS: | 1629268-00-3 | | MF: | C22H29ClN4O3 | | MW: | 432.94 | | EINECS: | | | Product Categories: | | | Mol File: | 1629268-00-3.mol |  |
| | ARS-853 Chemical Properties |
| Boiling point | 691.6±55.0 °C(Predicted) | | density | 1.357±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: 50 mg/ml | | form | A crystalline solid | | pka | 9.47±0.50(Predicted) | | color | White to off-white |
| | ARS-853 Usage And Synthesis |
| Uses | ARS-853 is an allele-specific inhibitor that inhibits KRASG12C signaling and cancer cell growth. | | IC 50 | KRAS(G12C): 2.5 μM (IC50) |
| | ARS-853 Preparation Products And Raw materials |
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