2,3-dihydro-2,3'-Bi-1H-indole

Request For Quotation
2,3-dihydro-2,3'-Bi-1H-indole Suppliers list
Company Name: Amadis Chemical Company Limited  
Tel: 571-89925085
Email: sales@amadischem.com
Company Name: TargetMol Chemicals Inc.  
Tel: +1-781-999-5354; +1-00000000000
Email: marketing@targetmol.com
Company Name: Hefei Hirisun Pharmatech Co., Ltd  
Tel: +8615056975894
Email: shawn@hirisunpharm.com
Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Company Name: Beijing Boorsen Biotechnology Co., Ltd  
Tel: 400-901-9800 18611424007
Email: cis@bioss.com.cn

2,3-dihydro-2,3'-Bi-1H-indole manufacturers

  • VPC-13163
  • VPC-13163 pictures
  • $48.00
  • 2026-06-08
  • CAS:6637-10-1
  • Purity: 98.02%
  • Supply Ability: 10g
2,3-dihydro-2,3'-Bi-1H-indole Basic information
Product Name:2,3-dihydro-2,3'-Bi-1H-indole
Synonyms:2,3-dihydro-2,3'-Bi-1H-indole;2,3'-Bi-1H-indole, 2,3-dihydro-;3'-Bi-1H-indole;3-dihydro-2;NSC 52361;NSC52361;VPC 13163;VPC13163
CAS:6637-10-1
MF:C16H14N2
MW:234.3
EINECS:
Product Categories:
Mol File:6637-10-1.mol
2,3-dihydro-2,3'-Bi-1H-indole Structure
2,3-dihydro-2,3'-Bi-1H-indole Chemical Properties
Melting point 110-111 °C
Boiling point 449.3±24.0 °C(Predicted)
density 1.225±0.06 g/cm3(Predicted)
pka16.68±0.30(Predicted)
Safety Information
MSDS Information
2,3-dihydro-2,3'-Bi-1H-indole Usage And Synthesis
DescriptionVPC-13163 has strong anti-proliferative activity against LNCaP and Enzalutamide-resistant prostate cancer cell lines (MR49F) whereas it did not affect the growth of AR independent PC3 cell line. It also inhibits Prostate Specific Antigen (PSA) in both LNCaP and MR49F and reduces expression of AR target genes, PSA and TMPRSS2. These findings suggest that VPC-13566 exhibits AR BF3 specific mechanism of action.
UsesVPC13163 is a potent androgen receptor (AR) BF3 inhibitor with an IC50 of 0.31 μM. VPC13163 has anticancer effects[1].
References[1] Ravi Shashi Nayana Munuganti, et al. Abstract 2508: The development of anti-androgens with a novel mechanism of action for treatment of castration-resistant prostate cancer. Cancer Res (2014) 74 (19_Supplement): 2508.
2,3-dihydro-2,3'-Bi-1H-indole Preparation Products And Raw materials
Raw materials10,15-Dihydro-5H-diindolo[3,2-a:3',2'-c]carbazole-->3-Bromoindole-->Indole
Tag:2,3-dihydro-2,3'-Bi-1H-indole(6637-10-1) Related Product Information
2-(Indolin-2-yl)-1H-indole 1H-Indole,5-fluoro-2,3-dihydro-2-(3-pyridinyl)-(9CI) 1H-Indole,2,3-dihydro-6,7-dimethyl-2-(3-pyridinyl)-(9CI) 1H-Indole,7-fluoro-2,3-dihydro-2-(3-pyridinyl)-(9CI) 1H-Indole,5,7-difluoro-2,3-dihydro-2-(3-pyridinyl)-(9CI) 1H-Indole,4-chloro-2,3-dihydro-7-methyl-2-(3-pyridinyl)-(9CI)