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| | Alectinib Intermediates Basic information |
| Product Name: | Alectinib Intermediates | | Synonyms: | Alectinib Impurity 7;6-Cyano-2-[1-[4-ethyl-3-[4-(4-morpholinyl)-1-piperidinyl]phenyl]-1-methylethyl]-1H-indole-3-carboxylic acid 1,1-dimethylethyl ester hydrochloride;tert-butyl 6-cyano-2-(2-(4-ethyl-3-(4-morpholinopiperidin-1-yl)phenyl)propan-2-yl)-1H-indole-3-carboxylate HCl;Aletinib Impurity 8(hydrochloride);tert-butyl 6-cyano-2-(2-{4-ethyl-3-[4-(morpholin-4-yl)piperidin-1-yl]phenyl}propan-2-yl)-1H-indole-3-carboxylate hydrochloride (1:1);6-Cyano-2-[1-[4-ethyl-3-[4-(4-morpholinyl)-1-piperidinyl]phenyl]-1-methylethyl]-1H-indole-3-carboxylic acid 1,1-dimethylethyl ester hydrochloride (1:1);tert-butyl 6-cyano-2-(2-(4-ethyl-3-(4-morpholinopiperidin-1-yl)phenyl)propan-2-yl)-1H-indole-3-carboxylate;tert-Butyl 6-Cyano-2-(2-(4-ethyl-3-(4-morpholinopiperidin-1-yl)phenyl)propan-2-yl)-1H-indole-3-carboxylate Hydrochloride | | CAS: | 1256584-77-6 | | MF: | C34H45ClN4O3 | | MW: | 593.21 | | EINECS: | | | Product Categories: | | | Mol File: | 1256584-77-6.mol |  |
| | Alectinib Intermediates Chemical Properties |
| InChIKey | VDZPTVLTFFGRJW-UHFFFAOYSA-N | | SMILES | C(C1C2=CC=C(C#N)C=C2NC=1C(C1C=CC(CC)=C(N2CCC(N3CCOCC3)CC2)C=1)(C)C)(=O)OC(C)(C)C.Cl |
| | Alectinib Intermediates Usage And Synthesis |
| Uses | tert-Butyl 6-Cyano-2-(2-(4-ethyl-3-(4-morpholinopiperidin-1-yl)phenyl)propan-2-yl)-1H-indole-3-carboxylate Hydrochloride is an intermediate of Alectinib (C183360), a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor capable of blocking the resistant gatekeeper mutant, which results in reduced cell growth. |
| | Alectinib Intermediates Preparation Products And Raw materials |
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