1H-Imidazo[4,5-c]quinolin-4-amine, 1-[[4-(aminomethyl)phenyl]methyl]-2-butyl- HCL

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1H-Imidazo[4,5-c]quinolin-4-amine, 1-[[4-(aminomethyl)phenyl]methyl]-2-butyl- HCL manufacturers

  • TLR7/8 agonist 1
  • TLR7/8 agonist 1 pictures
  • $48.00
  • 2026-07-31
  • CAS:1258457-59-8
  • Purity: 99.50%
  • Supply Ability: 10g
1H-Imidazo[4,5-c]quinolin-4-amine, 1-[[4-(aminomethyl)phenyl]methyl]-2-butyl- HCL Basic information
Product Name:1H-Imidazo[4,5-c]quinolin-4-amine, 1-[[4-(aminomethyl)phenyl]methyl]-2-butyl- HCL
Synonyms:1H-Imidazo[4,5-c]quinolin-4-amine, 1-[[4-(aminomethyl)phenyl]methyl]-2-butyl- HCL;1-(4-(aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-ylamine;1H-Imidazo[4,5-c]quinolin-4-amine, 1-[[4-(aminomethyl)phenyl]methyl]-2-butyl-;1-(4-(aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine hydrochloride;1-[[4-(aminomethyl)phenyl]methyl]-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine;1-[[4-(Aminomethyl)phenyl]methyl]-2-Butyl-Imidazo[4,5-C]quinolin-4-Amine;TLR7/8 agonist 7d;1-(4-(aminomethyl)benzyl)-2-butyl-1H-imidazolebenzo[4,5-c]quinoline-4-amine
CAS:1258457-59-8
MF:C22H25N5
MW:359.47
EINECS:
Product Categories:
Mol File:1258457-59-8.mol
1H-Imidazo[4,5-c]quinolin-4-amine, 1-[[4-(aminomethyl)phenyl]methyl]-2-butyl- HCL Structure
1H-Imidazo[4,5-c]quinolin-4-amine, 1-[[4-(aminomethyl)phenyl]methyl]-2-butyl- HCL Chemical Properties
Boiling point 633.3±55.0 °C(Predicted)
density 1.25±0.1 g/cm3(Predicted)
pka9.06±0.10(Predicted)
form Solid
color Off-white to light yellow
InChIInChI=1S/C22H25N5/c1-2-3-8-19-26-20-21(17-6-4-5-7-18(17)25-22(20)24)27(19)14-16-11-9-15(13-23)10-12-16/h4-7,9-12H,2-3,8,13-14,23H2,1H3,(H2,24,25)
InChIKeySDSKFWHQCNBICO-UHFFFAOYSA-N
SMILESN1C2C(=CC=CC=2)C2N(CC3=CC=C(CN)C=C3)C(CCCC)=NC=2C=1N
Safety Information
MSDS Information
1H-Imidazo[4,5-c]quinolin-4-amine, 1-[[4-(aminomethyl)phenyl]methyl]-2-butyl- HCL Usage And Synthesis
UsesTLR7/8 agonist 1 is a toll-like receptor (TLR7)/TLR8 dual-agonistic imidazoquinoline.
IC 50TLR7; TLR8
References[1] Shukla NM, et al. Syntheses of fluorescent imidazoquinoline conjugates as probes of Toll-like receptor 7. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6384-6. DOI:10.1016/j.bmcl.2010.09.093
[2] Beesu M, et al. Structure-Based Design of Human TLR8-Specific Agonists with Augmented Potency and Adjuvanticity. J Med Chem. 2015 Oct 8;58(19):7833-49. DOI:10.1021/acs.jmedchem.5b01087
1H-Imidazo[4,5-c]quinolin-4-amine, 1-[[4-(aminomethyl)phenyl]methyl]-2-butyl- HCL Preparation Products And Raw materials
Tag:1H-Imidazo[4,5-c]quinolin-4-amine, 1-[[4-(aminomethyl)phenyl]methyl]-2-butyl- HCL(1258457-59-8) Related Product Information
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