| Company Name: |
Zhengzhou Acme Chemical Co., Ltd.
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| Tel: |
0371-037163312495,13303845143 13303845143 |
| Email: |
3001379618@qq.com |
| Products Intro: |
Product Name:N-(m-PEG4)-N'-(amino-PEG3)-Cy5 Purity:98% Package:1g;5g;25g
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| | N-(m-PEG4)-N'-(amino-PEG3)-Cy5 Basic information |
| | N-(m-PEG4)-N'-(amino-PEG3)-Cy5 Chemical Properties |
| solubility | Soluble in Water, DMSO, DMF, DCM |
| | N-(m-PEG4)-N'-(amino-PEG3)-Cy5 Usage And Synthesis |
| Description | N-(m-PEG4)-N'-(amino-PEG3)-Cy5 TFA salt is a PEG linker containing a cyanine dye with excitation/emmission maximum 649/667 nm and a free amine group, which will be reactive with cabroxylic acid, activated NHS ester, carbonyl (ketone, aldehyde) etc. The hydophilic PEG spacer increases solubility in aqueous media. | | Uses | N-(m-PEG4)-N'-(amino-PEG3)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | N-(m-PEG4)-N'-(amino-PEG3)-Cy5 Preparation Products And Raw materials |
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