| Company Name: |
BOC Sciences |
| Tel: |
16314854226; +8616314854226 |
| Email: |
inquiry@bocsci.com |
Bamirastine manufacturers
- Bamirastine
-
- $700.00
-
2026-07-14
- CAS:215529-47-8
- Purity: 96.68%
- Supply Ability: 10g
- Bamirastine
-
- $700.00
-
2026-07-14
- CAS:215529-47-8
- Purity: 96.68%
- Supply Ability: 10g
- Bamirastine
-
- $700.00
-
2025-08-22
- CAS:215529-47-8
- Purity: 96.68%
- Supply Ability: 10g
|
| | Bamirastine Basic information |
| Product Name: | Bamirastine | | Synonyms: | Bamirastine;TAK-427;Imidazo[1,2-b]pyridazine-2-acetic acid, 6-[[3-[4-(diphenylmethoxy)-1-piperidinyl]propyl]amino]-α,α-dimethyl- | | CAS: | 215529-47-8 | | MF: | C31H37N5O3 | | MW: | 527.67 | | EINECS: | | | Product Categories: | | | Mol File: | 215529-47-8.mol |  |
| | Bamirastine Chemical Properties |
| Melting point | 109-112 °C | | density | 1.23±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | pka | 2.29±0.10(Predicted) |
| | Bamirastine Usage And Synthesis |
| Uses | Bamirastine inhibits ligand binding to recombinant human histamine H1 receptors (rhH1R) with an IC50 value of 17.3 nM. | | in vivo | Bamirastine (TAK-427) inhibits histamine induced skin reactions in guinea pigs and mice with an ID50 value of 0.884 and 0.450 mg/kg, p.o., respectively; significant inhibition associated with 10 mg/kg of Bamirastine is still observed 24 h after dosing in guinea pigs. Even at 300 mg/kg, Bamirastine does not affect pentobarbital-induced sleeping time in mice. Bamirastine significantly inhibits passive cutaneous anaphylaxis (PCA) in mice and guinea pigs, and also inhibits antigen-induced ISRs in guinea pigs[1]. | | References | [1] Fukuda S, et al. Characteristics of the antihistamine effect of TAK-427, a novel imidazopyridazine derivative. Inflamm Res. 2003 May;52(5):206-14. DOI:10.1007/s000110300073 |
| | Bamirastine Preparation Products And Raw materials |
|