DIETHYL-1,3,6,8-TETRAHYDRO-1,3,6,8-TETRAOXOBENZO[IMN][3,8]PHENANTHROLINE-2,7-DIACETATE

DIETHYL-1,3,6,8-TETRAHYDRO-1,3,6,8-TETRAOXOBENZO[IMN][3,8]PHENANTHROLINE-2,7-DIACETATE Suppliers list

Company Name:	TargetMol Chemicals Inc.
Tel:	+1-781-999-5354; +17819995354
Email:	marketing@targetmol.com
Products Intro:	Product Name:PPIase-Parvulin Inhibitor CAS:64005-90-9 Purity:98% Package:1mg;29USD\|2mg;39USD\|5mg;64USD Remarks:REAGENT;FOR LABORATORY USE ONLY

Company Name:	Aladdin Scientific
Tel:
Email:	tp@aladdinsci.com
Products Intro:	Product Name:PPIase-Parvulin inhibitor CAS:64005-90-9 Purity:>=95% Package:$190.9/10mg;Bulk package Remarks:95%

Company Name:	Perseverant (Tianjin) Biomedical Technology Co., Ltd Gold
Tel:	17777863707
Email:	17777863707@189.cn
Products Intro:	Product Name:diethyl 2,2'-(1,3,6,8-tetraoxo-1,3,6,8-tetrahydrobenzo[lmn][3,8]phenanthroline-2,7-diyl)diacetate CAS:64005-90-9 Purity:95%，98% Package:1g；100g；1kg

Company Name:	Shanghai ChuangYan Chemical Technology Co., Ltd.
Tel:	021-11111111 11111111111
Email:	546919421@qq.com
Products Intro:	Product Name:PPIase-Parvulin Inhibitor CAS:64005-90-9 Purity:95+ Package:1g

DIETHYL-1,3,6,8-TETRAHYDRO-1,3,6,8-TETRAOXOBENZO[IMN][3,8]PHENANTHROLINE-2,7-DIACETATE manufacturers

DIETHYL-1,3,6,8-TETRAHYDRO-1,3,6,8-TETRAOXOBENZO[IMN][3,8]PHENANTHROLINE-2,7-DIACETATE Basic information

Product Name:	DIETHYL-1,3,6,8-TETRAHYDRO-1,3,6,8-TETRAOXOBENZO[IMN][3,8]PHENANTHROLINE-2,7-DIACETATE
Synonyms:	PIB;DIETHYL-1,3,6,8-TETRAHYDRO-1,3,6,8-TETRAOXOBENZO[IMN][3,8]PHENANTHROLINE-2,7-DIACETATE;WNKQGFNIIHNGQM-UHFFFAOYSA-N;PPIase-Parvulin Inhibitor - CAS 64005-90-9 - Calbiochem;Benzo[lmn][3,8]phenanthroline-2,7-diacetic acid, 1,3,6,8-tetrahydro-1,3,6,8-tetraoxo-, 2,7-diethyl ester;PiB >=98% (HPLC);PPIase-Parvulin inhibitor,Inhibitor,PPIase Parvulin Inhibitor,PPIaseParvulin Inhibitor,inhibit;diethyl 2,2'-(1,3,6,8-tetraoxo-1,3,6,8-tetrahydrobenzo[lmn][3,8]phenanthroline-2,7-diyl)diacetate
CAS:	64005-90-9
MF:	C22H18N2O8
MW:	438.39
EINECS:
Product Categories:
Mol File:	Mol File

DIETHYL-1,3,6,8-TETRAHYDRO-1,3,6,8-TETRAOXOBENZO[IMN][3,8]PHENANTHROLINE-2,7-DIACETATE Chemical Properties

storage temp.	2-8°C
solubility	DMSO: soluble1-2mg/mL (warmed)
form	Brownish solid
color	white to light brown
InChI	InChI=1S/C18H18N2O8/c1-3-23-15(21)9-19-25-11-5-7-13-18-14(8-6-12(26-19)17(11)18)28-20(27-13)10-16(22)24-4-2/h5-8H,3-4,9-10H2,1-2H3
InChIKey	RUZSTTGSEVILES-UHFFFAOYSA-N
SMILES	C12=CC=C3C4C1=C(C=CC=4ON(CC(OCC)=O)O3)ON(CC(OCC)=O)O2

Safety Information

MSDS Information

DIETHYL-1,3,6,8-TETRAHYDRO-1,3,6,8-TETRAOXOBENZO[IMN][3,8]PHENANTHROLINE-2,7-DIACETATE Usage And Synthesis

Uses	PPIase-Parvulin inhibitor (compound B) is a cell-permeable inhibitor targeting PPIase Pin1 and Par14, with IC50s of 1.5 and 1.0 μM, respectively. PPIase-Parvulin inhibitor has anticancer activity and inhibits the growth and proliferation of mouse embryonic fibroblasts (MEFs)[1].
Biological Activity	PiB is an inhibitor of the peptidylprolyl isomerase Pin-1. Inhibition of Pin-1 leads to destabilization of the transcription factor Nanog, which is required for maintenance of embryonic stem cell cultures.
References	[1] Uchida T, et al. Pin1 and Par14 peptidyl prolyl isomerase inhibitors block cell proliferation. Chem Biol. 2003 Jan;10(1):15-24. DOI:10.1016/s1074-5521(02)00310-1

DIETHYL-1,3,6,8-TETRAHYDRO-1,3,6,8-TETRAOXOBENZO[IMN][3,8]PHENANTHROLINE-2,7-DIACETATE Preparation Products And Raw materials

Tag:DIETHYL-1,3,6,8-TETRAHYDRO-1,3,6,8-TETRAOXOBENZO[IMN][3,8]PHENANTHROLINE-2,7-DIACETATE(64005-90-9) Related Product Information

HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.