| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:JNJ-42259152
CAS:1301167-87-2
Package:25mg/RMB 10600
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| Company Name: |
BOC Sciences
|
| Tel: |
16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:JNJ-42259152
CAS:1301167-87-2
|
|
| | JNJ-42259152 Basic information |
| Product Name: | JNJ-42259152 | | Synonyms: | JNJ-42259152;Pyridine, 2-[[4-[1-(2-fluoroethyl)-4-(4-pyridinyl)-1H-pyrazol-3-yl]phenoxy]methyl]-3,5-dimethyl- | | CAS: | 1301167-87-2 | | MF: | C24H23FN4O | | MW: | 402.46 | | EINECS: | | | Product Categories: | | | Mol File: | 1301167-87-2.mol |  |
| | JNJ-42259152 Chemical Properties |
| Melting point | 138.8 °C | | Boiling point | 558.0±50.0 °C(Predicted) | | density | 1.19±0.1 g/cm3(Predicted) | | pka | 4.37±0.32(Predicted) |
| | JNJ-42259152 Usage And Synthesis |
| Uses | JNJ-42259152 is a phosphodiesterase 10A (PDE10A) positron emission tomography (PET) tracer that is specific for PDE10A activity. JNJ-42259152 can be dynamically scanned in healthy volunteers to assess its kinetic properties in the brain. The half-life of JNJ-42259152 in the blood is an average of 90 minutes. JNJ-42259152 has demonstrated reliable binding potential (BPND) in different target areas (such as the lentiform nucleus, caudate nucleus, ventral striatum, etc.), providing an important tool for studying neuropsychiatric diseases[1]. | | References | [1] Quantification of 18F-JNJ-42259152, a novel phosphodiesterase 10A PET tracer: kinetic modeling and test-retest study in human brain DOI:10.2967/jnumed.112.118679 |
| | JNJ-42259152 Preparation Products And Raw materials |
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