Tos-PEG4-acid manufacturers
- Tos-PEG4-acid
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- $46.00 / 5mg
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2026-01-05
- CAS:1453117-42-4
- Min. Order:
- Purity:
- Supply Ability: 10g
- Tos-PEG4-acid
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- $0.00 / 500mg
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2025-06-07
- CAS:1453117-42-4
- Min. Order: 500mg
- Purity: >97.00%
- Supply Ability: 500mg
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| | Tos-PEG4-acid Basic information |
| Product Name: | Tos-PEG4-acid | | Synonyms: | Tos-PEG4-acid;Propanoic acid, 3-[2-[2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]ethoxy]ethoxy]-;3-[2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethoxy]propanoic acid;3-[2-(2-{2-[(4-methylbenzenesulfonyl)oxy]ethoxy}ethoxy)ethoxy]propanoic acid | | CAS: | 1453117-42-4 | | MF: | C16H24O8S | | MW: | 376.42 | | EINECS: | | | Product Categories: | | | Mol File: | 1453117-42-4.mol |  |
| | Tos-PEG4-acid Chemical Properties |
| Boiling point | 548.3±50.0 °C(Predicted) | | density | 1.256±0.06 g/cm3(Predicted) | | storage temp. | Storage temp. 2-8°C | | form | Liquid | | pka | 4.27±0.10(Predicted) | | color | Colorless to light yellow |
| | Tos-PEG4-acid Usage And Synthesis |
| Description | Tos-PEG4-acid is a PEG linker containing a tosyl group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. | | Uses | Tos-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34. DOI:10.1038/s12276-018-0065-6 |
| | Tos-PEG4-acid Preparation Products And Raw materials |
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