- Boc-Lys-OH
-
- $0.00 / 25Kg/Drum
-
2026-05-23
- CAS:13734-28-6
- Min. Order: 1KG
- Purity: 98%min
- Supply Ability: 1000kgs
- Boc-L-Lys-OH
-
- $0.00 / 1kg
-
2026-05-22
- CAS:13734-28-6
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 1T+
|
| | Boc-Lys-OH Basic information |
| | Boc-Lys-OH Chemical Properties |
| Melting point | ~205 °C (dec.)(lit.) | | alpha | 22 º (c=2, CH3OH) | | Boiling point | 389.3°C (rough estimate) | | density | 1.1313 (rough estimate) | | refractive index | 21.5 ° (C=2, MeOH) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | Acetic Acid (Slightly), Methanol (Slightly, Sonicated), Water (Slightly, Heated, | | pka | 3.92±0.21(Predicted) | | form | Powder | | color | White | | Optical Rotation | [α]20/D +4.6±0.5°, c = 2% in H2O | | Water Solubility | Soluble in water. Slightly soluble in methanol. | | BRN | 4252546 | | Sequence | {Boc-Lys} | | Major Application | peptide synthesis | | InChI | InChI=1S/C11H22N2O4/c1-11(2,3)17-10(16)13-8(9(14)15)6-4-5-7-12/h8H,4-7,12H2,1-3H3,(H,13,16)(H,14,15)/t8-/m0/s1 | | InChIKey | DQUHYEDEGRNAFO-QMMMGPOBSA-N | | SMILES | C(O)(=O)[C@H](CCCCN)NC(OC(C)(C)C)=O | | CAS DataBase Reference | 13734-28-6(CAS DataBase Reference) |
| Hazard Codes | Xn | | Risk Statements | 20/21/22-36/37/38 | | Safety Statements | 24/25-36-26 | | WGK Germany | 3 | | HS Code | 2924 19 00 | | HazardClass | IRRITANT | | Storage Class | 11 - Combustible Solids |
| | Boc-Lys-OH Usage And Synthesis |
| Chemical Properties | white to off-white powder | | Uses | N-Boc-L-lysine is a protected analogue of a major amino acid participating in the binding of AcH to proteins. N-Boc-L-lysine as well as other t-butoxycarbonyl (Boc) amino acids can be converted to their respective amino acids via cleavage of the urethane bond. | | Uses | Boc-Lys-OH (Nα-Boc-L-lysine) can be used as a building block to synthesize: A heterotrifunctional peptide-based linker molecule applicable as a bio-labeling reagent. Lysine derivatives of azamacrocycle and anthraquinone. Boc-Lys(Bn4-DTPA)-OH, a precursor to synthesize diethylene triamine pentaacetic acid (DTPA) containing peptides. A ferrocene-amino acid conjugate which is used in developing chemical warfare agent (CWA) sensor.
| | Production Methods | L-lysine was added to acetone and Et3N under stirring at 25 °C. After that, di-tert-butyl dicarbonate was added. After 4.5 h, decompression evaporates acetone, and the water layer is extracted with ethyl ether 3 times. The dilute HC1 was added to the aqueous layer to adjust pH 2-3. The crude product was purified to obtain Boc-Lys-OH.
 | | reaction suitability | Boc solid-phase peptide synthesis | | References | [1] Patent: CN102993200, 2016, B. Location in patent: Paragraph 0050; 0051; 0052 [2] Journal of Materials Chemistry B, 2014, vol. 2, # 42, p. 7351 - 7359 [3] Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1995, vol. 34, # 1, p. 45 - 47 [4] Chinese Chemical Letters, 2012, vol. 23, # 3, p. 297 - 300 [5] Patent: CN103833623, 2016, B. Location in patent: Paragraph 0058; 0059; 0062 |
| | Boc-Lys-OH Preparation Products And Raw materials |
|