| Company Name: |
Alchem Pharmtech,Inc. |
| Tel: |
8485655694 |
| Email: |
sales@alchempharmtech.com |
| Products Intro: |
Product Name:7-Methyl-6,7,8,9-tetrahydro-[1,3]dioxolo[4',5':5,6]benzo[1,2-c][1,3]dioxolo[5',4':4,5]benzo[1,2-g]azecin-15(16H)-one
CAS:130-86-9
Purity:97+% Package:1g;10g;100g;;1kg Remarks:Z-33056
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- Protopine
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- $50.00
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2026-04-22
- CAS:130-86-9
- Purity: 99.25%
- Supply Ability: 10g
- Protopine
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2023-02-24
- CAS:130-86-9
- Min. Order: 5mg
- Purity: ≥98%(HPLC)
- Supply Ability: 10 g
- Protopine
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- $90.00
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2023-02-13
- CAS:130-86-9
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 100mt
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| | Protopine Basic information |
| Product Name: | Protopine | | Synonyms: | 7,13a-Secoberbin-13a-one, 7-methyl-2,3:9,10-bis(methylenedioxy)-;7-Methyl-6,8,9,16-tetrahydrodi[1,3]benzodioxolo[4,5-c:5,6-g]azecin-15(7H)-one;Biflorine;Bis[1,3]benzodioxolo[4,5-c:5',6'-g]azecin-13(5H)-one, 4,6,7,14-tetrahydro-5-methyl-;Hypercorine;Protopin;AKOS 243-72;5,7-DIHYDROXY-2-METHYLCHROMONE-6-C-BETA-D-GLUCOPYRANOSIDE | | CAS: | 130-86-9 | | MF: | C20H19NO5 | | MW: | 353.37 | | EINECS: | 204-999-6 | | Product Categories: | chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 130-86-9.mol |  |
| | Protopine Chemical Properties |
| Melting point | 203-205C | | Boiling point | 486.8°C (rough estimate) | | density | 1.399 (calc) | | refractive index | 1.5800 (estimate) | | storage temp. | Inert atmosphere,2-8°C | | Water Solubility | Insoluble in water | | solubility | DMSO : 12.5 mg/mL (35.37 mM; Need ultrasonic) | | pka | 7.86±0.20(Predicted) | | form | powder to crystal | | color | White to Light gray to Light yellow | | Major Application | food and beverages | | InChI | InChI=1S/C20H22NO5/c1-25-11-23-17-5-4-13-2-3-14-9-19-18(24-12-26(19)22)8-15(14)6-7-21-10-16(13)20(17)25/h2-5,8,16,21H,6-7,9-12H2,1H3/b13-2-,14-3- | | InChIKey | JVVZZYVMOGCQIP-JAIUMMMNSA-N | | SMILES | N1CCC2=CC3OCO(=O)C=3CC2=CC=C2C=CC3OCO(C)C=3C2C1 |c:14,t:16| | | LogP | 3.760 (est) | | NIST Chemistry Reference | Protopine(130-86-9) |
| Safety Statements | 24/25 | | RIDADR | 1544 | | WGK Germany | WGK 3 | | RTECS | VS2800000 | | HazardClass | 6.1(b) | | PackingGroup | III | | HS Code | 29391900 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral | | Hazardous Substances Data | 130-86-9(Hazardous Substances Data) | | Toxicity | guinea pig,LD50,intraperitoneal,116mg/kg (116mg/kg),Therapie. Vol. 28, Pg. 767, 1973. |
| | Protopine Usage And Synthesis |
| Chemical Properties | Off-White Solid | | Uses | Protopine is a Ca2+ channel blocker and antiplatelet agent. Immunomodulator | | Definition | ChEBI: A dibenzazecine alkaloid isolated from Fumaria vaillantii. | | General Description | This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG | | Purification Methods | It crystallises from EtOH/CHCl3. The picrate has m ~240o(dec). [Beilstein 27 H 558, 17 I 568, 17 II 620, 17 III/IV 6881.] |
| | Protopine Preparation Products And Raw materials |
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