- 5-Chlorovaleryl chloride
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- $10.00 / 1ASSAYS
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2025-11-02
- CAS:1575-61-7
- Min. Order: 1ASSAYS
- Purity: 99%
- Supply Ability: 10 ton
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| | 5-Chlorovaleryl chloride Chemical Properties |
| Boiling point | 38-39 °C0.15 mm Hg(lit.) | | density | 1.206 g/mL at 20 °C | | refractive index | n20/D 1.464(lit.) | | Fp | 195 °F | | storage temp. | Store below +30°C. | | solubility | Acetonitrile (Slightly), Chloroform (Sparingly) | | form | Liquid | | color | Clear colorless to slightly yellow | | Specific Gravity | 1.200 | | PH | <7 (H2O, 20℃) | | explosive limit | 2.0-10.2%(V) | | Water Solubility | reacts | | Sensitive | Moisture Sensitive | | BRN | 1745182 | | Stability: | Corrosive, Moisture Sensitive | | InChIKey | SVNNWKWHLOJLOK-UHFFFAOYSA-N | | CAS DataBase Reference | 1575-61-7(CAS DataBase Reference) |
| | 5-Chlorovaleryl chloride Usage And Synthesis |
| Description | 5-Chlorovaleryl chloride is an important synthetic intermediate of pyrazole herbicides. 5-Chloropentanoyl chloride is used as the raw material of 1,1,7-trichloro-1-hepten-3-one, and then the third-generation pyrazole herbicides can be synthesized. Pyrazole herbicides have the characteristics of ultra-efficient herbicidal activity, high selectivity, extremely low mammalian toxicity and good environmental characteristics, and have become a hot spot in the research and development of herbicides in the world in recent years. | | Chemical Properties | clear colourless to slightly yellow liquid | | Uses | 5-Chlorovaleroyl chloride (5-CVC) has been used in the development and validation of a GC-FID method for the analysis of low level impurities present in 5-CVC. It has been used in the synthesis of anion-exchange resins by acylation of polystyrene/divinylbenzene and subsequent amination with trimethylamine. It is commonly used as alkylating agent in the synthesis of pharmaceutical intermediates and other specialty chemicals. | | Application |
5-Chlorovaleryl chloride is an important medicine and pesticide intermediate. It is pharmaceutically mainly for the manufacture of the medicine Cilostazole (Cilostazol) for anti-platelet aggregation, protection of vascular endothelial cells, and atherosclerosis.5-Chlorovaleryl Chloride is also for the production of paddy rice New-type wide-spectrum weedicide pyraclonil (Pyraclonil).
| | General Description | 5-Chlorovaleroyl chloride is commonly used as alkylating agent in the synthesis of pharmaceutical intermediates and other specialty chemicals. | | Flammability and Explosibility | Not classified | | Synthesis |
In the existing process, producing 5-Chlorovaleryl chloride using 1,4-dichlorobutane as raw material requires a three-step reaction. First, 1,4-dichlorobutane and sodium cyanide solution are combined to form 5-chlorovaleronitrile. Then, the prepared 5-chlorovaleronitrile is hydrolyzed in concentrated hydrochloric acid to form 5-chlorovaleric acid. Finally, 5-chlorovaleronitrile reacts with thionyl chloride to generate 5-chlorovaleryl chloride.
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| | 5-Chlorovaleryl chloride Preparation Products And Raw materials |
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