N-(5-bromo-2-methoxybenzyl)tricyclo[3.3.1.1~3,7~]decan-1-amine

Request For Quotation
N-(5-bromo-2-methoxybenzyl)tricyclo[3.3.1.1~3,7~]decan-1-amine Suppliers list
Company Name: Shanghai YuanYe Biotechnology Co., Ltd.  
Tel: 15026964105
Email: 2881489226@qq.com
Company Name: Tianjin Kailiqi Biotechnology Co., Ltd.  
Tel: 15076683720
Email: klq@cw-bio.com
Company Name: BOC Sciences  
Tel: 16314854226; +8616314854226
Email: inquiry@bocsci.com
Company Name: TargetMol Chemicals Inc.  
Tel: +1-781-999-5354; +1-00000000000
Email: marketing@targetmol.com
Company Name: ChemeGen(Shanghai) Biotechnology Co.,Ltd.  
Tel: 18818260767
Email: sales@chemegen.com

N-(5-bromo-2-methoxybenzyl)tricyclo[3.3.1.1~3,7~]decan-1-amine manufacturers

  • ABMA
  • ABMA pictures
  • $30.00
  • 2026-05-26
  • CAS:332108-65-3
  • Purity: 99.86%
  • Supply Ability: 10g
  • ABMA
  • ABMA pictures
  • $30.00
  • 2026-05-26
  • CAS:332108-65-3
  • Purity: 99.86%
  • Supply Ability: 10g
  • ABMA
  • ABMA pictures
  • $30.00
  • 2026-05-26
  • CAS:332108-65-3
  • Purity: 99.86%
  • Supply Ability: 10g
N-(5-bromo-2-methoxybenzyl)tricyclo[3.3.1.1~3,7~]decan-1-amine Basic information
Product Name:N-(5-bromo-2-methoxybenzyl)tricyclo[3.3.1.1~3,7~]decan-1-amine
Synonyms:N-(5-bromo-2-methoxybenzyl)tricyclo[3.3.1.1~3,7~]decan-1-amine;Tricyclo[3.3.1.13,7]decan-1-amine, N-[(5-bromo-2-methoxyphenyl)methyl]-;N-(5-Bromo-2-methoxybenzyl)adamantan-1-amine;ABMA, 10 mM in DMSO;ABMA
CAS:332108-65-3
MF:C18H24BrNO
MW:350.29
EINECS:
Product Categories:
Mol File:332108-65-3.mol
N-(5-bromo-2-methoxybenzyl)tricyclo[3.3.1.1~3,7~]decan-1-amine Structure
N-(5-bromo-2-methoxybenzyl)tricyclo[3.3.1.1~3,7~]decan-1-amine Chemical Properties
Boiling point 428.2±30.0 °C(Predicted)
density 1.35±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: 125 mg/mL (356.85 mM)
pka9.86±0.20(Predicted)
form Solid
color White to off-white
Safety Information
MSDS Information
N-(5-bromo-2-methoxybenzyl)tricyclo[3.3.1.1~3,7~]decan-1-amine Usage And Synthesis
UsesABMA is a broad-spectrum inhibitor of intracellular toxins and pathogens. ABMA efficiently protects cells against various toxins and pathogens including viruses, intracellular bacteria and parasite. ABMA selectively acts at host cell late endosomes rather than targeting toxin or pathogen itself. ABMA has broad-spectrum anti-infection activity[1][2].
in vivo

ABMA (2-200 mg/kg; intraperitoneal injection; female BALB/c mice) treatment protects mice from nasal instillation of an LD90 of ricin[1].

Animal Model:Pathogen-free female BALB/c mice (6 week-old) with ricin[1]
Dosage:2 mg/kg, 20 mg/kg, 200 mg/kg
Administration:Intraperitoneal injection
Result:A statistically significant protection according to survival curves was observed with a single ip dose of 2mg/kg. The 20mg/kg dose fully protected animals through to day 21. The 200mg/kg dose resulted in 80% of protection of mice against ricin challenge with a single animal succumbing on day 15.
IC 50Leishmania
References[1] Wu Y, et al. ABMA, a small molecule that inhibits intracellular toxins and pathogens by interfering with late endosomal compartments. DOI:10.1038/s41598-017-15466-7
[2] Wu Y, et al. DABMA: A Derivative of ABMA with Improved Broad-Spectrum Inhibitory Activity of Toxins and Viruses. ACS Med Chem Lett. 2019 Jul 2;10(8):1140-1147. DOI:10.1021/acsmedchemlett.9b00155
N-(5-bromo-2-methoxybenzyl)tricyclo[3.3.1.1~3,7~]decan-1-amine Preparation Products And Raw materials
Tag:N-(5-bromo-2-methoxybenzyl)tricyclo[3.3.1.1~3,7~]decan-1-amine(332108-65-3) Related Product Information
CHEMBRDG-BB 5567768 Benzenemethanamine, 5-bromo-N-cyclopropyl-2-ethoxy- Benzenemethanamine, 2-methoxy-N-(1,1,3,3-tetramethylbutyl)- (S)-2-(5-Bromo-2-methoxyphenyl)piperidine 3-Pyrrolidinemethanol, 1-[(5-bromo-2-methoxyphenyl)methyl]- Benzenemethanamine, N-(1-cyclopropylethyl)-2-methoxy-