8-Bromo-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11(6H)-one

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8-Bromo-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11(6H)-one Basic information
Product Name:8-Bromo-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11(6H)-one
Synonyms:Desloratadine 8-Bromo-11-oxo;11H-Benzo[5,6]cyclohepta[1,2-b]pyridin-11-one, 8-bromo-5,6-dihydro-;N1,N1-diethyl-3-methylbenzene-1,4-diamine hydrochloride;8-Bromo-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11(6H)-one
CAS:143540-56-1
MF:C14H10BrNO
MW:288.14
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Mol File:143540-56-1.mol
8-Bromo-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11(6H)-one Structure
8-Bromo-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11(6H)-one Chemical Properties
Boiling point 445.8±45.0 °C(Predicted)
density 1.518±0.06 g/cm3(Predicted)
solubility soluble in Chloroform
pka3.14±0.20(Predicted)
form Powder
color Greenish
Safety Information
MSDS Information
8-Bromo-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11(6H)-one Usage And Synthesis
Uses8-Bromo-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one is an intermediate in the synthesis of 8-Deschloro-8-bromo Desloratadine (D290995), an impurity of Loratadine (L469575). 8-Deschloro-8-bromo Desloratadine may be usedto develop novel analytical applications for detecting impurities ofLoratadine.
8-Bromo-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11(6H)-one Preparation Products And Raw materials
Tag:8-Bromo-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11(6H)-one(143540-56-1) Related Product Information
8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one 9-Bromo-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11(6H)-one 3-BroMo-8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one 5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one Loratadine Impurity 13 11H-Benzo[5,6]cyclohepta[1,2-b]pyridin-11-one, 3,10-dibromo-8-chloro-5,6-dihydro-