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| | 1-METHYL-1-CYCLOHEXANECARBOXYLIC ACID Basic information |
| | 1-METHYL-1-CYCLOHEXANECARBOXYLIC ACID Chemical Properties |
| Melting point | 36-39 °C(lit.) | | Boiling point | 234 °C(lit.) | | density | 1.0037 (rough estimate) | | refractive index | 1.4600 (estimate) | | Fp | 213 °F | | storage temp. | Sealed in dry,Room Temperature | | solubility | Soluble in chloroform and methanol. | | pka | pK1:5.13 (25°C) | | form | Solid | | color | Brown | | BRN | 1859220 | | InChI | InChI=1S/C8H14O2/c1-8(7(9)10)5-3-2-4-6-8/h2-6H2,1H3,(H,9,10) | | InChIKey | REHQLKUNRPCYEW-UHFFFAOYSA-N | | SMILES | C1(C)(C(O)=O)CCCCC1 | | CAS DataBase Reference | 1123-25-7(CAS DataBase Reference) |
| Hazard Codes | Xi | | Safety Statements | 24/25 | | WGK Germany | 3 | | RTECS | GU8585500 | | Hazard Note | Irritant | | HS Code | 29162000 | | Storage Class | 11 - Combustible Solids | | Toxicity | mouse,LD50,intraperitoneal,860mg/kg (860mg/kg),BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)BEHAVIORAL: ATAXIA,Neuropharmacology. Vol. 24, Pg. 427, 1985. |
| | 1-METHYL-1-CYCLOHEXANECARBOXYLIC ACID Usage And Synthesis |
| Chemical Properties | WHITE TO YELLOW CRYSTALS OR CRYSTALLINE POWDER | | Uses | 1-Methyl-1-cyclohexanecarboxylic acid was used as internal standard during the determination of valproic acid metabolites. Also been used as an anticonvulsant drug and causes maturation of murine neuroblastoma cells in vitro. Used in the synthesis of p38 map kinase. | | Synthesis Reference(s) | The Journal of Organic Chemistry, 38, p. 3633, 1973 DOI: 10.1021/jo00960a047 | | General Description | 1-Methyl-1-cyclohexanecarboxylic acid is the structural analog of valproic acid and its pharmacokinetic action has been studied in female Sprague-Dawley rats. | | Biochem/physiol Actions | 1-Methyl-1-cyclohexanecarboxylic acid is an anticonvulsant drug and causes maturation of murine neuroblastoma cells in vitro. |
| | 1-METHYL-1-CYCLOHEXANECARBOXYLIC ACID Preparation Products And Raw materials |
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