1,3-DIOXANE

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CAS:505-22-6
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  • 1,3-DIOXANE
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  • 2025-09-25
  • CAS:505-22-6
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  • Purity: 99%
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  • 2021-07-02
  • CAS:505-22-6
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1,3-DIOXANE Basic information
Product Name:1,3-DIOXANE
Synonyms:1,3-Dioxacyclohexane;1,3-Propanediol formal;1,3-propanediolformal;dihydro-m-dioxi;m-Dioxin, dihydro-;meta-dioxane;trimethyleneglycolmethyleneether;M-DIOXANE
CAS:505-22-6
MF:C4H8O2
MW:88.11
EINECS:208-005-1
Product Categories:Dioxanes;Dioxanes & Dioxolanes
Mol File:505-22-6.mol
1,3-DIOXANE Structure
1,3-DIOXANE Chemical Properties
Melting point -45 °C (lit.)
Boiling point 105-106 °C (lit.)
density 1.032 g/mL at 25 °C (lit.)
refractive index n20/D 1.418(lit.)
Fp 59 °F
storage temp. Flammables area
form clear liquid
color Colorless to Almost colorless
Water Solubility Fully miscible in water.
BRN 102532
Stability:Stable. Flammable. Incompatible with oxidizing agents. May form explosive peroxides in contact with the air - store under inert gas.
InChIInChI=1S/C4H8O2/c1-2-5-4-6-3-1/h1-4H2
InChIKeyVDFVNEFVBPFDSB-UHFFFAOYSA-N
SMILESO1CCCOC1
EPA Substance Registry System1,3-Dioxane (505-22-6)
Safety Information
Hazard Codes F,Xn
Risk Statements 11-20/21/22
Safety Statements 16
RIDADR UN 1165 3/PG 2
WGK Germany 3
RTECS JG8224000
HS Code 2932.99.9090
HazardClass 3.1
PackingGroup II
Storage Class3 - Flammable liquids
Hazard ClassificationsAcute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Flam. Liq. 2
Hazardous Substances Data505-22-6(Hazardous Substances Data)
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
1,3-DIOXANE Usage And Synthesis
Chemical Propertiescolourless liquid
Uses1,3-Dioxane has been employed as solvent in the synthesis of 8- and 9-membered dioxazocines and dioxazonines.
DefinitionChEBI: 1,3-dioxane is a dioxane and a cyclic acetal.
Preparation1,3-dioxane is prepared by the reaction of formaldehyde and 1,3-propanediol in the presence of Br?nsted or Lewis acid catalysts.
General DescriptionClear colorless liquid.
Air & Water ReactionsHighly flammable. Can form dangerous peroxides when exposed to air. Water soluble.
Reactivity Profile1,3-DIOXANE is sensitive to heat. 1,3-DIOXANE can react with oxidizers.
Health HazardACUTE/CHRONIC HAZARDS: When heated to decomposition 1,3-DIOXANE emits acrid smoke and fumes.
Fire Hazard1,3-DIOXANE is flammable.
Purification MethodsDry the dioxane with sodium and fractionally distil it. [Beilstein 19/1 V 11.]
Tag:1,3-DIOXANE(505-22-6) Related Product Information
1,3-Dioxan-2-one 2-(2-Bromoethyl)-1,3-dioxane 2,4,8,10-TETRAOXASPIRO[5.5]UNDECANE 1,2:3,5-Di-O-isopropylidene-alpha-D-xylofuranose 3,9-Divinyl-2,4,8,10-tetraoxaspiro[5.5]undecane 5,5-DIMETHYL-1,3-DIOXAN-2-ONE 4-PHENYL-1,3-DIOXANE 1,3-DIOXANE 2,2,5-Trimethyl-1,3-dioxane-4,6-dione 2-(1,3-Dioxan-2-yl)ethyltriphenylphosphonium bromide 1,4-Cyclohexanedione mono(2,2-dimethyltrimethylene ketal) 2,2-DIMETHYL-5-PHENYL-1,3-DIOXANE-4,6-DIONE Glycerol formal 4-METHYL-1,3-DIOXANE 4,6-O-Ethylidene-alpha-D-glucose METHYL 4,6-O-BENZYLIDENE-ALPHA-D-GLUCOPYRANOSIDE 1-(1,4-Benzodioxane-2-carbonyl)piperazine 2,2-Dimethyl-1,3-dioxane-4,6-dione

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