[1-[(3-chlorophenyl)methyl]indol-3-yl]methanol

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[1-[(3-chlorophenyl)methyl]indol-3-yl]methanol manufacturers

  • Oncrasin-72
  • Oncrasin-72 pictures
  • $1980.00
  • 2026-05-11
  • CAS:92407-90-4
  • Purity:
  • Supply Ability: 10g
[1-[(3-chlorophenyl)methyl]indol-3-yl]methanol Basic information
Product Name:[1-[(3-chlorophenyl)methyl]indol-3-yl]methanol
Synonyms:[1-[(3-chlorophenyl)methyl]indol-3-yl]methanol;NSC 743380;NSC743380;NSC-743380;Oncrasin 72;Oncrasin72;Oncrasin-72;Oncrasin-72 NSC-743380
CAS:92407-90-4
MF:C16H14ClNO
MW:271.74146
EINECS:
Product Categories:
Mol File:92407-90-4.mol
[1-[(3-chlorophenyl)methyl]indol-3-yl]methanol Structure
[1-[(3-chlorophenyl)methyl]indol-3-yl]methanol Chemical Properties
form Solid
color White to off-white
Safety Information
MSDS Information
[1-[(3-chlorophenyl)methyl]indol-3-yl]methanol Usage And Synthesis
DescriptionOncrasin-72 is an analogue of oncrasin-1 with antitumor activity mediated by JNK activation and STAT3 inhibition.
UsesOncrasin-72 (NSC-743380) is an RNA polymerase II inhibitor with activity in inhibiting growth and inducing cell death in human cancer cells. Oncrasin-72 exhibits antitumor activity through JNK activation and STAT3 inhibition. Analytical method development and validation for Oncrasin-72 is essential for quantifying its concentration in biological fluids for pharmacokinetic studies. This method was able to successfully quantify Oncrasin-72 in different dose groups when applied in rat plasma[1].
References[1] Simultaneous determination and validation of oncrasin-266 and its metabolites by HPLC-MS/MS: Application to a pharmacokinetic study DOI:10.1016/j.jchromb.2016.07.033
[1-[(3-chlorophenyl)methyl]indol-3-yl]methanol Preparation Products And Raw materials
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