1,2,3,4-Tetrahydrocarbazole

1,2,3,4-Tetrahydrocarbazole Suppliers list

Company Name:	TCI (Shanghai) Development Co., Ltd.
Tel:	021-67121386
Email:	Sales-CN@TCIchemicals.com

1,2,3,4-Tetrahydrocarbazole manufacturers

1,2,3,4-Tetrahydrocarbazole Basic information

Product Name:	1,2,3,4-Tetrahydrocarbazole
Synonyms:	,3,4,9-Tetrahydro-1H-carbazole;1H-Indole, 2,3-(1,4-butanediyl)-;2,3,4,9-tetrahydro-1h-carbazol;2,3-Tetramethylene-1H-indole;5,6,7,8-tetrahydro-carbazol;5,6,7,8-Tetrahydrocarbazole;Carbazole, 1,2,3,4-tetrahydro-;Carbazole, 5,6,7,8-tetrahydro-
CAS:	942-01-8
MF:	C12H13N
MW:	171.24
EINECS:	213-385-7
Product Categories:	Building Blocks;Chemical Synthesis;Heterocyclic Building Blocks;Building Blocks;Carbazoles;Heterocyclic Building Blocks
Mol File:	942-01-8.mol

1,2,3,4-Tetrahydrocarbazole Chemical Properties

Melting point	118-120 °C (lit.)
Boiling point	325-330 °C (lit.)
density	1.1459 (rough estimate)
refractive index	1.6544 (estimate)
Fp	325-330°C
storage temp.	Sealed in dry,Room Temperature
form	powder to crystal
pka	17.84±0.20(Predicted)
color	White to Orange to Green
Water Solubility	Insoluble in water. Solubility in methanol (almost transparency).
BRN	133771
InChI	1S/C12H13N/c1-3-7-11-9(5-1)10-6-2-4-8-12(10)13-11/h1,3,5,7,13H,2,4,6,8H2
InChIKey	XKLNOVWDVMWTOB-UHFFFAOYSA-N
SMILES	C1CCc2c(C1)[nH]c3ccccc23
CAS DataBase Reference	942-01-8(CAS DataBase Reference)
NIST Chemistry Reference	1H-Carbazole, 2,3,4,9-tetrahydro-(942-01-8)

Safety Information

MSDS Information

1,2,3,4-Tetrahydrocarbazole Usage And Synthesis

Synthesis	In a 100 mL three-necked flask, phenylhydrazine hydrochloride (1.44 g, 10 mmol) was added in portions over 30 minutes to a 30 mL solution of cyclohexanone (1.00 g, 10 mmol) in acetic acid. The mixture was then refluxed for 8 hours until the reaction was complete. The reaction was cooled to room temperature and then poured into ice water. The solid was collected by filtration and recrystallized from methanol to give intermediate 1,2,3,4-tetrahydrocarbazole as a white solid, 1.44 g, yield 85%.
Chemical Properties	beige crystalline powder
Uses	It finds its application as a pharmaceutical intermediate and in the synthesis of aspidospermidine alkaloids.
Uses	1,2,3,4-Tetrahydrocarbazole can be used as a starting material to prepare: Spiro[cyclopentane-1,2′-indolin-3′-one] by photooxygenation. 9-Acyl-1,2,3,4-tetrahydrocarbazoles by N-acylation reactions. Carbazole via palladium-catalyzed asymmetric hydrogenation reaction.
Synthesis Reference(s)	Chemical and Pharmaceutical Bulletin, 14, p. 934, 1966 DOI: 10.1248/cpb.14.934 Tetrahedron Letters, 26, p. 161, 1985 DOI: 10.1016/S0040-4039(00)61869-5

1,2,3,4-Tetrahydrocarbazole Preparation Products And Raw materials

Preparation Products

Tag:1,2,3,4-Tetrahydrocarbazole(942-01-8) Related Product Information

Tetramethylammonium hydroxide pentahydrate cis-1,2,3,6-Tetrahydrophthalic anhydride Methyl tetrahydrophthalic anhydride Tetrahydrothiophene Tetrahydrofuran POLY(N-VINYLCARBAZOLE) carbazol-4-one hydrochloride 4-OXO-1,2,3,4-TETRAHYDROCARBAZOLE 6-CHLORO-1 2 3 4-TETRAHYDROCARBAZOLE 9&,6-CHLORO-1,2,3,4-TETRAHYDROCARBAZOLE, 98 % N-METHYL-4-OXO-1,2,3,4-TETRAHYDROCARBAZOLE 3-Dimethylaminomethyl-1,2,3,4-tetrahydro-9-methylcarbazol-4-one 3-Amino-1,2,3,4-tetrahydrocarbazol 4-OXO-1,2,3,4-TETRAHYDROCARBAZOLE Carbazole (S)-3-Amino-1,2,3,4-tetrahydrocarbazole N-BENZYL-1,2,3,4-TETRAHYDROCARBAZOLE 3-METHYL-1,2,3,4-TETRAHYDROCARBAZOLE 1,2,3,4-TETRAHYDROCARBAZOLE-1-ONE