Peptide C105Y
| 中文名称 | Peptide C105Y |
|---|---|
| 中文同义词 | H-CYS-SER-ILE-PRO-PRO-GLU-VAL-LYS-PHE-ASN-LYS-PRO-PHE-VAL-TYR-LEU-ILE-OH;多肽C105Y |
| 英文名称 | Peptide C105Y |
| 英文同义词 | Peptide C105Y;L-Isoleucine, L-cysteinyl-L-seryl-L-isoleucyl-L-prolyl-L-prolyl-L-α-glutamyl-L-valyl-L-lysyl-L-phenylalanyl-L-asparaginyl-L-lysyl-L-prolyl-L-phenylalanyl-L-valyl-L-tyrosyl-L-leucyl-;C105Y;Peptide C105Y、[Cys58]105Y, α1-antitrypsin (358-374) |
| CAS号 | 247572-63-0 |
| 分子式 | C97H148N20O23S |
| 分子量 | 1994.43 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 247572-63-0.mol |
| 结构式 |  |
Peptide C105Y 性质
| 沸点 | 2033.5±65.0 °C(Predicted) |
|---|---|
| 密度 | 1.275±0.06 g/cm3(Predicted) |
| 酸度系数(pKa) | 3.41±0.10(Predicted) |
| 序列 | Cys-Ser-Ile-Pro-Pro-Glu-Val-Lys-Phe-Asn-Lys-Pro-Phe-Val-Tyr-Leu-Ile |
Peptide C105Y，基于 α1-抗胰蛋白酶 359-374 残基氨基酸序列合成的细胞穿透性肽，能增强 DNA 纳米粒的基因表达。
When human hepatoma cells (HuH7) were incubated with fluorescently labeled C105Y for as little as 3 min, C105Y displays nuclear and cytoplasmic staining with enrichment of fluorescent signal in the nucleus and nucleolus. C105Y peptide is routed to the nucleolus very rapidly in an energy-dependent fashion, whereas membrane translocation and nuclear localization are energy-independent. When tested the involvement of known endocytosis pathways in uptake and trafficking of this peptide, C105Y peptide is internalized by a clathrin- and caveolin-independent pathway, although lipid raft-mediated endocytosis may play a role in peptide intracellular trafficking.
安全信息
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2023/03/20 | HY-P1781 | Peptide C105Y Peptide C105Y | 247572-63-0 | 5mg | 4000元 |
| 2023/03/20 | HY-P1781 | Peptide C105Y Peptide C105Y | 247572-63-0 | 10mg | 6800元 |