- [Leu5]-Enkephalin
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![[Leu5]-Enkephalin pictures](/ProductImageEN1/2025-09/Small/abd6a7f9-bd04-4cb8-b907-1d5ca94fbf04.png)
- $40.00 / 10mg
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2025-09-11
- CAS:58822-25-6
- Min. Order:
- Purity: 99.88%
- Supply Ability: 10g
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| | [LEU5]-ENKEPHALIN Basic information |
| Product Name: | [LEU5]-ENKEPHALIN | | Synonyms: | [Leu5]-Enkephalin,Tyr-Gly-Gly-Phe-Leu,YGGFL,ICI-114740,Leu-enkephalin,Leucine enkephalin,Leucyl-enkephalin?, BR;leucine enkephalin acetate hydrate;(5-LEUCINE)ENKEPHALIN 96+%;L-Tyr-Gly-Gly-L-Phe-L-Leu-OH;Tyr-Gly-Gly-Phe-Leu-OH;Leu-Enkelphalin Tyr-Gly-Gly-Phe-Leu;L-TYR-GLY-GLY-PHE-LEU;LEUCINE-ENKEPHALIN (HUMAN, PORCINE, BOVINE, RAT, MOUSE) | | CAS: | 58822-25-6 | | MF: | C28H37N5O7 | | MW: | 555.62 | | EINECS: | 261-457-1 | | Product Categories: | Pepetides;peptides;Peptide;Opioid receptor and opioid-like receptor;58822-25-6 | | Mol File: | 58822-25-6.mol | ![[LEU5]-ENKEPHALIN Structure](CAS/GIF/58822-25-6.gif) |
| | [LEU5]-ENKEPHALIN Chemical Properties |
| Melting point | 130-133 °C | | alpha | +32.3°(c=9,メタノール) | | Boiling point | 998.8±65.0 °C(Predicted) | | density | 1.274±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Sealed in dry,Store in freezer, under -20°C | | solubility | ≥54.6 mg/mL in H2O; ≥54.8 mg/mL in EtOH; ≥55.6 mg/mL in DMSO | | form | Lyophilized powder | | pka | 3.40±0.10(Predicted) | | color | White to light yellow | | Water Solubility | Soluble in water (1 mg/ml ). | | Sequence | H-Tyr-Gly-Gly-Phe-Leu-OH | | InChIKey | URLZCHNOLZSCCA-VABKMULXSA-N | | SMILES | C(O)(=O)[C@H](CC(C)C)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(=O)[C@H](CC1=CC=C(O)C=C1)N |
| | [LEU5]-ENKEPHALIN Usage And Synthesis |
| Uses | Endogenous opioid neurotransmitter/neuromodulator that is an agonist at ? and δ opioid receptors, localization in brain parallels the localization of δ receptors. | | Definition | ChEBI: Leu-enkephalin is a pentapeptide comprising L-tyrosine, glycine, glycine, L-phenylalanine and L-leucine residues joined in sequence by peptide linkages. It is an endogenous opioid peptide produced in vertebrate species, including rodents, primates and humans that results from decomposition of proenkephalin or dynorphin and exhibits antinociceptive properties. It has a role as a delta-opioid receptor agonist, a mu-opioid receptor agonist, a neurotransmitter, an analgesic, a human metabolite and a rat metabolite. It is functionally related to a L-tyrosine, a glycine, a L-phenylalanine and a L-leucine. It is a tautomer of a Leu-enkephalin zwitterion. | | IC 50 | Human Endogenous Metabolite | | storage | Store at -20°C |
| | [LEU5]-ENKEPHALIN Preparation Products And Raw materials |
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