BCRP-IN-1

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BCRP-IN-1 Suppliers list
Company Name: Shanghai YuanYe Biotechnology Co., Ltd.  
Tel: 15026964105
Email: 2881489226@qq.com
Company Name: Beijing Solarbio Science & Tecnology Co., Ltd.  
Tel: 17801761073 18101056239
Email: 3193328036@qq.com
Company Name: Fan De(Beijing) Biotechnology Co., Ltd.  
Tel: 15911056312
Email: liming@bio-fount.com
Company Name: BOC Sciences  
Tel: 16314854226; +8616314854226
Email: inquiry@bocsci.com
Company Name: TargetMol Chemicals Inc.  
Tel: +1-781-999-5354; +1-00000000000
Email: marketing@targetmol.com

BCRP-IN-1 manufacturers

  • (S)-ML753286
  • (S)-ML753286 pictures
  • $523.00
  • 2026-05-11
  • CAS:1699720-85-8
  • Purity:
  • Supply Ability: 10g
  • (S)-ML753286
  • (S)-ML753286 pictures
  • $523.00
  • 2025-10-28
  • CAS:1699720-85-8
  • Purity:
  • Supply Ability: 10g
BCRP-IN-1 Basic information
Product Name:BCRP-IN-1
Synonyms:BCRP-IN-1;(S)-ML753286;Pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, 2,3,6,7,12,12a-hexahydro-9-methoxy-3-methyl-6-(2-methylpropyl)-, (3S,6S,12aS)-;(S) ML753286,(S)-ML-753286,(S)ML753286
CAS:1699720-85-8
MF:C20H25N3O3
MW:355.43
EINECS:
Product Categories:
Mol File:1699720-85-8.mol
BCRP-IN-1 Structure
BCRP-IN-1 Chemical Properties
Boiling point 638.0±55.0 °C(Predicted)
density 1.27±0.1 g/cm3(Predicted)
pka13.65±0.60(Predicted)
form Solid
color White to light yellow
Safety Information
MSDS Information
BCRP-IN-1 Usage And Synthesis
Uses(S)-ML753286 is a breast cancer resistance protein (BCRP) inhibitor with an IC50 of 0.6 μM on BCRP efflux transporter.
in vivo

(S)-ML753286 (Compound A) shows the potency and a potent pharmacokinetic (PK) profile in rats (lower clearance [1.54 L/h/kg] and higher bioavailability [123%]). XL388 has moderate terminal elimination half-life with t1/2s of 0.9 h and 2.0 h for 2 mg/kg (iv) and 20 mg/kg (po) in rats, respectively[1].

References[1] Li Y, et al. Synthesis of a new inhibitor of breast cancer resistance protein with significantly improved pharmacokinetic profiles. Bioorg Med Chem Lett. 2016 Jan 15;26(2):551-555. DOI:10.1016/j.bmcl.2015.11.077
BCRP-IN-1 Preparation Products And Raw materials
Tag:BCRP-IN-1(1699720-85-8) Related Product Information
Pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, 2-amino-6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-, (6S,12aR)- ABCG2-IN-1 (3S)-Methyl 1-isobutyl-7-Methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate 1-isobutyl-7-Methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole Pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-, (6R,12aR)-rel- N-Octyl Nortadalafil