N-METHYLISATIN

N-METHYLISATIN Suppliers list

Company Name:	ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Tel:	+86-13017695106 +86-13676922317
Email:	jiuyitime@fdachem.com
Products Intro:	Product Name:1-methylisatin CAS:2058-74-4 Purity:99%min Package:100kg;2.2USD\|10kg;6.6USD\|1kg;8.8USD

Company Name:	Hefei Lbao Physical & Chemical Science Co.,Ltd
Tel:	+1-5184799099
Email:	lbaochemicals@gmail.com
Products Intro:	Product Name:1-Methylisatin CAS:2058-74-4 Purity:98%

Company Name:	Accela ChemBio Inc.
Tel:	+1-858-6993322
Email:	info@accelachem.com
Products Intro:	Product Name:1-Methylisatin CAS:2058-74-4 Purity:>=97% Package:1g;5g;10g;25g;100g

Company Name:	Alchem Pharmtech,Inc.
Tel:	8485655694
Email:	sales@alchempharmtech.com
Products Intro:	Product Name:1-Methylindoline-2,3-dione CAS:2058-74-4 Purity:97+% Package:1g;10g;100g;;1kg Remarks:Z-02798

Company Name:	CONIER CHEM AND PHARMA LIMITED
Tel:	+8618523575427
Email:	sales@conier.com
Products Intro:	CAS:2058-74-4 Purity:0.99 Package:1kg

N-METHYLISATIN manufacturers

N-METHYLISATIN Basic information

Product Name:	N-METHYLISATIN
Synonyms:	187287;1-methylindoline-2,3-dione;1-Methyl-2,3-dihydro-1H-indole-2,3-dione;OL-57;N-Methylindol-2,3-dione;1-Methylisatin,98%;N-Methylindoline-2,3-dione;1-Methyl-1H-indole-2,3-dione, 1-Methylindolin-2,3-dione
CAS:	2058-74-4
MF:	C9H7NO2
MW:	161.16
EINECS:	218-164-9
Product Categories:	Heterocycles;Building Blocks;Heterocyclic Building Blocks;Indoles;pharmacetical
Mol File:	2058-74-4.mol

N-METHYLISATIN Chemical Properties

Melting point	130-133 °C (lit.)
Boiling point	287.44°C (rough estimate)
density	1.314
refractive index	1.5050 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
pka	-2.41±0.20(Predicted)
form	Crystalline Powder
color	Orange to brownish
Water Solubility	Insoluble in water.
λmax	427nm(CH2Cl2)(lit.)
BRN	128280
InChI	InChI=1S/C9H7NO2/c1-10-7-5-3-2-4-6(7)8(11)9(10)12/h2-5H,1H3
InChIKey	VCYBVWFTGAZHGH-UHFFFAOYSA-N
SMILES	N1(C)C2=C(C=CC=C2)C(=O)C1=O
CAS DataBase Reference	2058-74-4(CAS DataBase Reference)

Safety Information

Hazard Codes	T
Risk Statements	25-37/38-41
Safety Statements	26-39-45
RIDADR	UN 2811 6.1/PG 3
WGK Germany	3
RTECS	NL7939000
HazardClass	IRRITANT
HS Code	29337900
Toxicity	mouse,LD50,intraperitoneal,685mg/kg (685mg/kg),LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION,Pharmaceutical Chemistry Journal Vol. 15, Pg. 858, 1981.

MSDS Information

N-METHYLISATIN Usage And Synthesis

Chemical Properties	ORANGE TO BROWNISH CRYSTALLINE POWDER
Uses	1-Methylisatin is used as a reactant for stereoselective preparation of spirobicyclic and bis-spirotricyclic pyrazolidinones, for regioselective preparation of spirocyclic oxindole-butenolides, for synthesis of spiro-oxindoles, for preparation of unsymmetrical oxindoles, for stereoselective preparation of hydroxyloxindoles via Morita-Baylis-Hillman reaction, for preparation of pyridinecarboxylic acid [(oxo)indolylidene)hydrazide derivatives (Schiff base hydrazides) as antibacterial agents.
Uses	Reactant for stereoselective preparation of spirobicyclic and bis-spirotricyclic pyrazolidinones Reactant for regioselective preparation of spirocyclic oxindole-butenolides Reactant for synthesis of spiro-oxindoles Reactant for preparation of unsymmetrical oxindoles Reactant for stereoselective preparation of hydroxyloxindoles via Morita-Baylis-Hillman reaction Reactant for preparation of pyridinecarboxylic acid [(oxo)indolylidene)hydrazide derivatives (Schiff base hydrazides) as antibacterial agents
Synthesis Reference(s)	Journal of Medicinal Chemistry, 47, p. 2089, 2004 DOI: 10.1021/jm030483s
General Description	The interaction between 1-methylisatin and human adult haemoglobin was studied using the circular dichroism (CD) spectroscopic, anisotropy and FTIR investigations.
IC 50	hiCE: 38.2 μM (Ki); hCE1: 5.38 μM (Ki)

N-METHYLISATIN Preparation Products And Raw materials

Raw materials	2-Butynamide, N-methyl-N-phenyl--->2-Propynamide, N-methyl-N-phenyl--->2-Propenamide,N-methyl-N,3-diphenyl--->Acetamide, N-methyl-2-(methylphenylamino)--->2-Propynamide, N-methyl-N,3-diphenyl--->1-Methylindoline-->4-Acetylbenzoic acid-->1-METHYL-2-INDOLINONE-->Ethanone, 1-[2-(methylamino)phenyl]- (9CI)-->Isatin-->1-benzyl-5-iodoindoline-2,3-dione-->5-iodo-1-methylindoline-2,3-dione
Preparation Products	2-Thiophenecarboxylic acid-->5-METHYL-1,2,4-TRIAZINO[5,6-B]INDOLE-3-THIOL-->1-METHYL-1H-INDOLE-2,3-DIONE 3-[N-(4-CHLOROPHENYL)HYDRAZONE]-->(7Z)-3-(4-fluorophenyl)-7-(1-methyl-2-oxoindol-3-ylidene)-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-6-one

Tag:N-METHYLISATIN(2058-74-4) Related Product Information

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