| | DELTA-8-THC Basic information |
| Product Name: | DELTA-8-THC | | Synonyms: | Δ8-THC (CRM);(-)-delta(sup8)-trans-tetrahydrocannabinol;(-)-trans-delta(sup8)-tetrahydrocannabinol;1-trans-delta(sup8)-tetrahydro-cannabino;1-trans-delta(sup8)-tetrahydrocannabinol;d)pyran-1-ol,6a,7,10,10a-tetrahydro-3-pentyl-6,6,9-trimethyl-6h-dibenzo(tr;d)pyran-1-ol,6a,7,10,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-6h-dibenzo(;delta(sup6)-thc | | CAS: | 5957-75-5 | | MF: | C21H30O2 | | MW: | 314.46 | | EINECS: | 637-364-0 | | Product Categories: | Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 5957-75-5.mol |  |
| | DELTA-8-THC Chemical Properties |
| alpha | D18 -264° (c = 0.11 in ethanol) | | Boiling point | bp0.001 200° | | density | 1.0536 (rough estimate) | | refractive index | 1.5404 (estimate) | | Fp | 11 °C | | storage temp. | −20°C | | solubility | DMF: 50 mg/ml
DMF: PBS (pH 7.2)(1:3): 250 µg/ml
DMSO: 60 mg/ml
Ethanol: 35 mg/ml
Methanol: 30 mg/ml | | form | ethanol solution | | pka | 9.83±0.60(Predicted) |
| | DELTA-8-THC Usage And Synthesis |
| Uses | It is one of the active constituent of cannabis. Agonist at CB1 and CB2 cannabinoid receptors. Antiemetic; appetite stimulant. Controlled substance (hallucinogen). | | Definition | ChEBI: Delta8-THC is a 1-benzopyran. | | References | [1] MATHANGI KRISHNAMURTHY Bob M I M Antonio M Ferreira. Synthesis and Testing of Novel Phenyl Substituted Side-Chain Analogues of Classical Cannabinoids.[J]. ChemInform, 2004, 35 4. DOI: 10.1002/chin.200404143
[2] DINESH THAPA. The Cannabinoids Δ8THC, CBD, and HU-308 Act via Distinct Receptors to Reduce Corneal Pain and Inflammation.[J]. Cannabis and Cannabinoid Research, 2018, 3 1: 11-20. DOI: 10.1089/can.2017.0041
[3] LIESL K. JANSSENS. Investigation of the intrinsic cannabinoid activity of hemp-derived and semisynthetic cannabinoids with β-arrestin2 recruitment assays—and how this matters for the harm potential of seized drugs[J]. Archives of Toxicology, 2024, 98 8: 2619-2630. DOI: 10.1007/s00204-024-03769-4
[4] JOHN MERRICK. Identification of Psychoactive Degradants of Cannabidiol in Simulated Gastric and Physiological Fluid.[J]. Cannabis and Cannabinoid Research, 2016, 1 1: 102-112. DOI: 10.1089/can.2015.0004 |
| | DELTA-8-THC Preparation Products And Raw materials |
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