DBCO-NH-Boc manufacturers
- DBCO-NH-Boc
-
- $30.00 / 2mg
-
2025-08-21
- CAS:1539290-74-8
- Min. Order:
- Purity:
- Supply Ability: 10g
|
| | DBCO-NH-Boc Basic information |
| Product Name: | DBCO-NH-Boc | | Synonyms: | DBCO-NH-Boc;Carbamic acid, N-[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]-, 1,1-dimethylethyl ester;DBDBCO-NH-Boc;Carbamic acid,N-[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]-, 1,1-dimethylethyl ester (ACI) | | CAS: | 1539290-74-8 | | MF: | C23H24N2O3 | | MW: | 376.45 | | EINECS: | | | Product Categories: | | | Mol File: | 1539290-74-8.mol |  |
| | DBCO-NH-Boc Chemical Properties |
| Boiling point | 622.0±55.0 °C(Predicted) | | density | 1.22±0.1 g/cm3(Predicted) | | storage temp. | Storage temp. 2-8°C | | solubility | Soluble in DMSO, DCM, DMF | | pka | 12.25±0.46(Predicted) | | form | Solid | | color | White to yellow |
| | DBCO-NH-Boc Usage And Synthesis |
| Description | DBCO-NH-Boc is a click chemistry reagent with a DBCO group. DBCO can undergo copper-free Click Chemistry reactions with azides. | | Uses | DBCO-NH-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-NH-Boc is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. | | IC 50 | Alkyl/ether | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | DBCO-NH-Boc Preparation Products And Raw materials |
|