- Isoflupredone Acetate
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- $32.00 / 1mg
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2026-01-26
- CAS:338-98-7
- Min. Order:
- Purity: 99.43%
- Supply Ability: 10g
- Isoflupredone Acetate
-
- $32.00 / 1kg
-
2025-09-25
- CAS:338-98-7
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
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| | Isoflupredone Acetate Basic information |
| | Isoflupredone Acetate Chemical Properties |
| Melting point | 244-246° (dec) | | alpha | D23 +108° (c = 0.735 in dioxane) | | Boiling point | 576.5±50.0 °C(Predicted) | | density | 1.32±0.1 g/cm3(Predicted) | | storage temp. | -20°C Freezer | | solubility | Acetone (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly), Ethanol (Slightly) | | pka | 12.05±0.70(Predicted) | | form | Solid | | color | White to Off-White | | InChIKey | ZOCUOMKMBMEYQV-BZIJPSHGNA-N | | SMILES | [C@@]12([H])CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@]1(C)[C@@](CC[C@@]21[H])(O)C(=O)COC(=O)C |&1:0,10,12,14,17,19,22,r| |
| | Isoflupredone Acetate Usage And Synthesis |
| Uses | Isoflupredone Acetate is an anti-inflammatory drug used in veterinary medicine. It is a corticosteroid with both glucocorticoid and mineralocorticoid activity and has been shown to increase the frequency of severe hypokalemia in healthy cows. | | Definition | ChEBI: 9alpha-Fluoro-11beta,17alpha,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate is a corticosteroid hormone. | | Veterinary Drugs and Treatments | Isoflupredone acetate is a potent glucocorticoid and like other glucocorticoids
can be used for its antiinflammatory or immunosuppressive
effects. Labeled indications for isoflupredone include: adjunctive
treatment of bovine ketosis, alleviating pain and lameness
associated with musculoskeletal conditions, acute hypersensitivity
reactions, adjunctive treatment of overwhelming infections with
severe toxicity, shock, supportive therapy in the treatment of stress
conditions (e.g., surgery), dystocia, retained placenta, inflammatory
ocular conditions, snakebite and parturient paresis.
In horses, isoflupredone has been used parenterally to reduce
inflammation associated with recurrent airway obstruction (RAO,
“heaves”, COPD).
While the drug could be used in small animals, it is recommended
to use other glucocorticoid agents instead, where there has been
more experience and other approved products for dogs and cats are
available. | | in vivo | Isoflupredone acetate (0.05 mg/kg; i.m.; on days 2 and 4 after the challenge) prevents dry-matter intake and average daily gain reductions, and leads to faster Mannheimia haemolytica-infected clinical improvement when co-treated with Oxytetracycline.html" class="link-product" target="_blank">Oxytetracycline (HY-B0275)[2]. | Animal Model: | 96 weanling heifers (Bronchopneumonia was induced by intrabronchial infusion of Mannheimia haemolytica)[2] | | Dosage: | 0.05 mg/kg | | Administration: | i.m.; on days 2 and 4 after the challenge | | Result: | Infection caused a reduction in dry-matter intake and average daily gain (ADG) in heifers.
Prevented these reductions and resulted in faster clinical improvement when co-treated with Oxytetracycline (HY-B0275). |
| | Toxics Screening Level | The ITSL for Isoflupredone Acetate is 0.01 μg/m3 based on annual averaging. |
| | Isoflupredone Acetate Preparation Products And Raw materials |
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