| Company Name: |
shlmai |
| Tel: |
021-67680335 13052188602 |
| Email: |
sale1@shlmai.net |
|
| Product Name: | ANXA2 | | Synonyms: | ANXA2;Recombinant Human Annexin A2/ANXA2 Protein, No Tag | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANXA2 Structure]() |
| | ANXA2 Chemical Properties |
| | ANXA2 Usage And Synthesis |
| Description | ANXA2 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 376 amino acids (1-339a.a.) and having a molecular mass of 42.8 kDa. ANXA2 is fused to a 37 amino acid His-Tag at N-Terminus and purified by proprietary chromatographic techniques. | | Source | Escherichia Coli | | Background | ANXA2 is part of the annexin family and is involved in the regulation of cellular growth and in signal transduction pathways. ANXA2 protein functions as an autocrine factor which increases osteoclast formation and bone resorption. ANXA2 is associated with sickle cell osteonecrosis. Reduced ANXA2 expression is associated with osteosarcoma metastases. ANXA2 is part of the putative cell surface vitamin D binding protein binding site complex and functions to mediate the chemotactic cofactor effect. ANXA2 is involved in dysferlin deficiency and in muscular dystrophies. Human colon adenocarcinoma cell differentiation is related with an up-regulation of ANXA2. |
| | ANXA2 Preparation Products And Raw materials |
|