Benzo[f][1,7]naphthyridine-8-propanoic acid, 5-amino-2-[2-[4-[2-(3,3-difluoro-3-phosphonopropoxy)ethoxy]-2-methylphenyl]ethyl]-

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Benzo[f][1,7]naphthyridine-8-propanoic acid, 5-amino-2-[2-[4-[2-(3,3-difluoro-3-phosphonopropoxy)ethoxy]-2-methylphenyl]ethyl]- Basic information
Product Name:Benzo[f][1,7]naphthyridine-8-propanoic acid, 5-amino-2-[2-[4-[2-(3,3-difluoro-3-phosphonopropoxy)ethoxy]-2-methylphenyl]ethyl]-
Synonyms:Benzo[f][1,7]naphthyridine-8-propanoic acid, 5-amino-2-[2-[4-[2-(3,3-difluoro-3-phosphonopropoxy)ethoxy]-2-methylphenyl]ethyl]-;LHC-165;LHC 165,LHC165
CAS:1258595-14-0
MF:C29H32F2N3O7P
MW:603.55
EINECS:
Product Categories:
Mol File:1258595-14-0.mol
Benzo[f][1,7]naphthyridine-8-propanoic acid, 5-amino-2-[2-[4-[2-(3,3-difluoro-3-phosphonopropoxy)ethoxy]-2-methylphenyl]ethyl]- Structure
Benzo[f][1,7]naphthyridine-8-propanoic acid, 5-amino-2-[2-[4-[2-(3,3-difluoro-3-phosphonopropoxy)ethoxy]-2-methylphenyl]ethyl]- Chemical Properties
Boiling point 829.8±75.0 °C(Predicted)
density 1.414±0.06 g/cm3(Predicted)
storage temp. Store at -20°C, stored under nitrogen
solubility 1M NaOH : 50 mg/mL (82.84 mM; ultrasonic and adjust pH to 12 with NaOH)
form Solid
pka1.19±0.10(Predicted)
color Light yellow to yellow
Safety Information
MSDS Information
Benzo[f][1,7]naphthyridine-8-propanoic acid, 5-amino-2-[2-[4-[2-(3,3-difluoro-3-phosphonopropoxy)ethoxy]-2-methylphenyl]ethyl]- Usage And Synthesis
UsesLHC-165 is a TLR7 agonist. LHC-165 has potential to used in study of solid tumors[1][2].
IC 50TLR7
References[1] Carole Bourquin, et al. Harnessing the immune system to fight cancer with Toll-like receptor and RIG-I-like receptor agonists. Pharmacological Research. 2019 Mar.
[2] LHC165.
Benzo[f][1,7]naphthyridine-8-propanoic acid, 5-amino-2-[2-[4-[2-(3,3-difluoro-3-phosphonopropoxy)ethoxy]-2-methylphenyl]ethyl]- Preparation Products And Raw materials
Tag:Benzo[f][1,7]naphthyridine-8-propanoic acid, 5-amino-2-[2-[4-[2-(3,3-difluoro-3-phosphonopropoxy)ethoxy]-2-methylphenyl]ethyl]-(1258595-14-0) Related Product Information
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