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NSJ Bioreagents |
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Biosynth Ltd |
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Abmart Inc |
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| Product Name: | BAP31 antibody | | Synonyms: | BAP31 antibody;Rabbit Monoclonal BAP31 Antibody | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![BAP31 antibody Structure]() |
| | BAP31 antibody Chemical Properties |
| | BAP31 antibody Usage And Synthesis |
| Source | Rabbit | | Reactivity | Human;Mouse;Rat;Monkey | | Background | BAP31 is a transmembrane protein associated with the endplasmic reticulum and ER-Golgi intermediates and has been implicated in protein trafficking and apoptosis. During apoptosis Bap31 is cleaved by caspase-8 at two carboxy-terminal sites which can then direct apoptotic signals between the ER and mitochondria. Association of BAP31 with the anti-apoptotic proteins Bcl-2 or Bcl-xL could function to regulate this ER-mitochondrial pathway. Several studies have shown that BAP31 can control the trafficking of select proteins between the ER and Golgi apparatus and can affect the transport of proteins to the cell surface. | | References | [1] Adachi, T. et al. (1996) EMBO J 15, 1534-41.
[2] Ng, F.W. et al. (1997) J Cell Biol 139, 327-38.
[3] Breckenridge, D.G. et al. (2003) J Cell Biol 160, 1115-27.
[4] Chandra, D. et al. (2004) Mol Cell Biol 24, 6592-607.
[5] Ng, F.W. and Shore, G.C. (1998) J Biol Chem 273, 3140-3.
[6] Annaert, W.G. et al. (1997) J Cell Biol 139, 1397-410.
[7] Lambert, G. et al. (2001) J Biol Chem 276, 20340-5.
[8] Schamel, W.W. et al. (2003) Proc Natl Acad Sci USA 100, 9861-6.
[9] Paquet, M.E. et al. (2004) J Immunol 172, 7548-55.
[10] Szczesna-Skorupa, E. and Kemper, B. (2006) J Biol Chem 281, 4142-8. |
| | BAP31 antibody Preparation Products And Raw materials |
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