| Company Name: |
Shanghai Universal Biotech Co.,Ltd
|
| Tel: |
15921930842 15921930842 |
| Email: |
yh-wang@univ-bio.com |
| Products Intro: |
Product Name:Cleaved Caspase-3 (Asp175) Antibody
Package:300ul/RMB 100
|
| Company Name: |
Cell Signaling Technology Inc
|
| Tel: |
21-80243558 86218024 |
| Email: |
info@cellsignal.cn |
| Products Intro: |
Product Name:Cleaved Caspase-3 (Asp175) Antibody
|
|
| | Cleaved Caspase-3 (Asp175) Antibody Chemical Properties |
| | Cleaved Caspase-3 (Asp175) Antibody Usage And Synthesis |
| Source | Rabbit | | Reactivity | Human;Mouse;Rat;Monkey | | Background | Caspase-3 is a critical executioner of apoptosis, as it is either partially or totally responsible for the proteolytic cleavage of many key proteins, such as the nuclear enzyme poly polymerase. Activation of caspase-3 requires proteolytic processing of its inactive zymogen into activated p17 and p12 fragments. Cleavage of caspase-3 requires the aspartic acid residue at the P1 position. | | References | [1] Fernandes-Alnemri, T. et al. (1994) J Biol Chem 269, 30761-4.
[2] Nicholson, D.W. et al. (1995) Nature 376, 37-43. |
| | Cleaved Caspase-3 (Asp175) Antibody Preparation Products And Raw materials |
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